Using advanced biotechnological techniques to improve cannabis cultivars

Shujat, Salma; Robinson, Gregory Ian; Norouzkhani, Farzaneh; Kovalchuk, Igor

doi:10.1016/j.bcab.2024.103250

Cited by 3 publications

(1 citation statement)

References 197 publications

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“…Additionally, cannabis micropropagation allows for rapid multiplication while maintaining genetic integrity. Integrating gene editing methods to modify RNA and regulate gene expression within cannabis offers further tools to precisely control or modify biosynthetic pathways, thereby achieving desired cannabis characteristics [170] . However, the biosynthetic origin and genetic regulation of many potentially therapeutically relevant compounds is still unknown, limiting the possibilities of controlling biochemical pathways, as metabolic engineering in yeast and cell-free platforms are not yet compatible with commercial-scale production, while molecular pharming through the development of cell cultures is complicated by the complexity of cannabinoids at low molar concentrations [188] …”

Section: The Plant’s Chemical Constitutionmentioning

confidence: 99%

In the weeds: A comprehensive review of cannabis; its chemical complexity, biosynthesis, and healing abilities

Laaboudi,

Rejdali,

Amhamdi

et al. 2024

Toxicology Reports

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Section: The Plant’s Chemical Constitutionmentioning

confidence: 99%

In the weeds: A comprehensive review of cannabis; its chemical complexity, biosynthesis, and healing abilities

Laaboudi,

Rejdali,

Amhamdi

et al. 2024

Toxicology Reports

View full text Add to dashboard Cite

Morpho-anatomical, phytochemical, and molecular diversity of North-Indian Cannabis sativa L. germplasms for CBD-rich genotypes

Ghosh,

Kundu,

Chaudhary

et al. 2024

Nucleus

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Illuminating Cannabis sativa L.: The Power of Light in Enhancing C. sativa Growth and Secondary Metabolite Production

Ahsan,

Injamum-Ul-Hoque,

Shaffique

et al. 2024

Plants

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Light is crucial for higher plants, driving photosynthesis and serving as a powerful sensory signal that profoundly modulates growth, development, physiological functions, hormone activation, and biochemical pathways. Various light parameters—quality, intensity, composition, and photoperiod—exert a tremendous influence on plant growth and development, particularly in industrial hemp (Cannabis sativa L.). C. sativa, a crop of historical significance and unparalleled versatility, holds immense value in the food, fiber, and medicinal industries. The cultivation of medicinal cannabis is burgeoning in controlled environments due to evolving healthcare regulations. Optimal light conditions significantly enhance both yield and harvest quality, notably increasing the density of apical inflorescences and the ratio of inflorescence to total aboveground biomass. C. sativa metabolites, especially phenolic and terpene compounds and Phytocannabinoids like CBD (cannabidiol), THC (tetrahydrocannabinol), and CBG (cannabigerol), possess immense medicinal value. Secondary metabolites in C. sativa predominantly accumulate in the trichomes of female flowers and surrounding sugar leaves, underscoring the critical need to boost inflorescence weight and metabolite concentrations while ensuring product consistency. Different light parameters distinctly impact C. sativa’s metabolic profile, providing a robust foundation for understanding the optimal conditions for synthesizing specific secondary metabolites. While the effects of light measurement on various crops are well-established, scientific evidence specifically relating to light quality effects on C. sativa morphology and secondary metabolite accumulation remains scarce. In this review, we critically summarized how different light properties can alter cannabis growth (vegetative and reproductive), physiology and metabolism. Furthermore, the mechanisms by which specific wavelengths influence growth, development, and secondary metabolite biosynthesis in C. sativa are not fully elucidated, which could be a prospective task for future researchers. Our review paves the way for a profound understanding of light’s influence on C. sativa growth and advancements in greenhouse settings to maximize metabolite production for commercial use.

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Using advanced biotechnological techniques to improve cannabis cultivars

Cited by 3 publications

References 197 publications

In the weeds: A comprehensive review of cannabis; its chemical complexity, biosynthesis, and healing abilities

In the weeds: A comprehensive review of cannabis; its chemical complexity, biosynthesis, and healing abilities

Morpho-anatomical, phytochemical, and molecular diversity of North-Indian Cannabis sativa L. germplasms for CBD-rich genotypes

Illuminating Cannabis sativa L.: The Power of Light in Enhancing C. sativa Growth and Secondary Metabolite Production

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