Using fetal MRI to define normal development of the cerebellum and vermis

Read, C.P.; Ramus, Ronald M.; McIntire, Donald D.; Twickler, Diane M.

doi:10.1016/j.ajog.2004.10.494

Cited by 1 publication

(2 citation statements)

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“…A total of 804 studies were initially screened and 59 publications were included in the final systematic review 4,5,7,15‐69 (Figure 1) (Table S1). Separate publications with duplicated data from those included were assessed 51,70‐80 …”

Section: Resultsmentioning

confidence: 99%

“…The latter was shown to be positively correlated elsewhere however 18,39,51 . In total, 15 measurements and six angles (such as TVA) were unaffected by GA. Studies comparing CM depth, lateral ventricle transverse diameter, CSOA, and inferior vermian distance (craniocaudal) with GA have been inconsistent in their findings 15,18,19,21,25,26,28,39,44,51,52,54,61,63 …”

Section: Resultsmentioning

confidence: 99%

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Biometric assessments of the posterior fossa by fetal MRI: A systematic review

et al. 2020

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Background Posterior fossa abnormalities (PFAs) are commonly identified within routine screening and are a frequent indication for fetal magnetic resonance imaging (MRI). Although biometric measurements of the posterior fossa (PF) are established on fetal ultrasound and MRI, qualitative visual assessments are predominantly used to differentiate PFAs. Objectives This systematic review aimed to assess 2‐dimensional (2D) biometric measurements currently in use for assessing the PF on fetal MRI to delineate different PFAs. Methods The protocol was registered (PROSPERO ID CRD42019142162). Eligible studies included T2‐weighted MRI PF measurements in fetuses with and without PFAs, including measurements of the PF, or other brain areas relevant to PFAs. Results 59 studies were included – 6859 fetuses had 62 2D PF and related measurements. These included linear, area and angular measurements, representing measures of PF size, cerebellum/vermis, brainstem, and supratentorial measurements. 11 measurements were used in 10 or more studies and at least 1200 fetuses. These dimensions were used to characterise normal for gestational age, diagnose a range of pathologies, and predict outcome. Conclusion A selection of validated 2D biometric measurements of the PF on fetal MRI may be useful for identification of PFA in different clinical settings. Consistent use of these measures, both clinically and for research, is recommended.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%