Using injectable fillers for midface rejuvenation

Abstract

Treatment aimed at preventing and reversing the facial aging process has grown in popularity. The aging midface is defined by classic deepening of the nasolabial folds, formation of marionette lines around the mouth, and significant atrophy of deep facial fat. While surgical options have been investigated with satisfactory and longlasting results, nonsurgical alternatives such as soft tissue fillers are a safe and effective strategy for facial rejuvenation. This review focuses on a variety of injectable fillers available for the treatment of the aging midface, including hyaluronic acid, calcium hydroxylapatite, poly-L-lactic acid, and polymethyl methacrylate. Mechanism of action, relevant anatomy, indications/contraindications, technique, and any evidence of efficacy and safety are described. The benefits of injectable fillers include reduced patient discomfort and shorter recovery times. Understanding the advantages and limitations of injectable fillers for midface augmentation can allow providers to counsel and treat patients seeking care appropriately.

An Update on the Clinical Efficacy and Safety of Collagen Injectables for Aesthetic and Regenerative Medicine Applications

“…In the case of aesthetic surgery, fillers would be less costly than surgical rhytidectomy ($15,181) in cases of small facial area. In cases of large volume, the medical cost for surgery would be the lowest cost option among the other treatments over the course of several years [ 1 ].…”

“…Indeed, as preparation and administration techniques have become increasingly standardized, the frequency of post-injection complications has also decreased. Moreover, the selection of the appropriate filler, which depends on patient factors, including degree of volume loss, disease, age, cost, preference, and surgical candidacy was revealed to be crucial for the implant success [ 1 ], underscoring the need for product-specific training. Regardless of materials safety, appropriate handling and adequate experience are mandatory for minimizing the risk of complications and achieving the desired effect.…”

“…The popularity of minimally invasive techniques increased rapidly for several reasons. A principal factor is the acceptance of soft tissue fillers among patients that are not ready for permanent treatments [ 1 ]. In the case of patients not wishing to undergo surgery, an easier procedure would generally be more accepted.…”

“…In the case of patients not wishing to undergo surgery, an easier procedure would generally be more accepted. Moreover, compared to undergoing more invasive surgery, fillers offer the patient less discomfort and a shorter recovery time, making them very practical in the resolution of minor-serious disease and allowing patients to return immediately to their daily routine [ 1 , 2 ]. Minimally invasive therapies would give a better quality of life also for that part of population that would otherwise not survive the trauma induced by conventional surgeries.…”

From Nasolabial Folds to Pan-facial Rejuvenation—The Evolution of Fillers in my Career

“…The aging process often leads to effects that ultimately contribute to a decrease in jawline definition such as increased skin laxity, loss of volume in the lower face fat pads, and bone resorption. 15,16 Additionally, chin ptosis commonly occurs as a result of soft tissue laxity. 15,16 Noninvasive injectable fillers can restore volume loss as well as enhance jawline contour.…”