Using the intact periosteum for horizontal bone augmentation of peri-implant defects: a retrospective cohort study

Chen, Deng; Yi, Zumu; Xiong, Chenyi; Man, Yi; Qu, Yi

doi:10.1016/j.bjoms.2022.09.012

Cited by 3 publications

(4 citation statements)

References 24 publications

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“…Combining the scRNA-seq and ST, we're able to identify the key markers of PCs subsets and dissecting functional PCs subpopulations. Here, we constructed a subperiosteal bone grafting model inspired by clinical procedures (20). We mapped the rat PCs at single-cell resolution and identify the heterogeneity within the jaw bone PCs.…”

Section: Discussionmentioning

confidence: 99%

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Spp1 secreted by macrophages impairs osteogenic ability of Ctsk⁺Fmod⁺periosteal cells in jaw bone

Liu

Wang

et al. 2023

Preprint

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Periosteum, which covers the surface of most bones, mediates bone regeneration through endochondral ossification during fracture repair and intramembranous ossification under steady state. Periosteal cells (PCs) of jaw bones are different from those of long bones in phenotypic characteristics and functions. So far, the role of periosteum in jaw bones during bone grafting remain unclarified. Here we propose a subperiosteal bone grafting model based on the clinical procedures. By integrating single-cell RNA sequencing (scRNA-seq) and spatial transcriptomic (ST), we found a functional Ctsk+Fmod+ subset of PCs in jaw bones. The Ctsk+Fmod+ PCs had the potential of multi-directional differentiation. Furthermore, Spp1 secreted by macrophages could impair the osteogenic capacity of Ctsk+Fmod+ PCs, which could be partly rescued by blocking Spp1. The identification of this Ctsk+Fmod+ subclusters, which shows osteoprogenitor characteristics and close interaction with macrophages, reveals the heterogeneity of periosteal cells in jaw bones, and may provide target of intervention to improve osteogenesis during bone augmentation surgery.

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Section: Discussionmentioning

confidence: 99%

“…were analyzed (20). Histological analysis of samples taken 6 months after surgery suggested that there was new bone formation underlying the periosteum.…”

Section: Establishment Of Subperiosteal Bone Grafting Modelmentioning

confidence: 99%

Spp1 secreted by macrophages impairs osteogenic ability of Ctsk⁺Fmod⁺periosteal cells in jaw bone

Liu

Wang

et al. 2023

Preprint

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“…They allow expansion and simultaneous implant placement without introducing bone graft materials relying solely on the periosteum. The periosteum preservation also helped stabilize the ridge split fracture and reduced the resorption of bony plates and marginal bone [ 10 ]. It takes advantage of the inherent quality of flexibility of cancellous bone.…”

Section: Discussionmentioning

confidence: 99%

A Modified Ridge-Splitting Technique to Restore a Completely Edentulous Maxillary Arch With a Cement-Retained Implant Prosthesis

Rahhal,

Awad,

Fayyad

et al. 2023

Cureus

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The present report describes a technique in which the maxillary bone was molded to the desired location using a series of instruments for ridge-splitting procedures. This technique aims to improve bone quality all around the implants at both the crest and apex locations. In some clinical scenarios, insufficient horizontal bone with less than 3 mm prevents implant placement. Thus, ridge splitting is a treatment of choice, and this technique creates bone expansion to form a better receptor site for endosteal implants. A case report is presented involving a completely edentulous 52-year-old male patient presented to the clinic with a horizontal bone defect. The patient complained of having difficulty eating and wants to improve his smile. In this clinical case, a modified ridge-splitting technique was employed, differing from the conventional procedure that uses mallets, chisels, or osteotomes. A lancet and spatula were used for precise ridge splitting, followed by the placement of four endosseous tapered implants-two on each side (Dentis USA, La Palma, USA). Each implant had a diameter of 3.7 mm and a length of 10 mm. These implants were clinically placed in a single visit, with a torque of 30 N/cm² applied to ensure secure fixation. To accommodate the patient's unique maxillary bone anatomy, 25-degree angulated abutments were chosen for the four implants, ensuring a common path of insertion, and optimal angulation for long-term stability and aesthetics. Subsequently, a cemented provisional dental prosthesis restoration was fitted, and the patient reported satisfaction with both function and aesthetics. After a period of five months of osseointegration, the stability of the implants was assessed using a resonance frequency analyzer, yielding positive results. The average resonance frequency values for the maxillary left (canine and premolar) were ISQ 68 and ISQ 71, respectively, while for the maxillary right (lateral incisor and premolar), the values were ISQ 69 and ISQ 73. These readings indicate satisfactory implant stability following the osseointegration process. The postoperative cone-beam computed tomography (CBCT) showed gain to the bone width besides better function and good results concerning the esthetics. This report describes a modified ridge-splitting technique with a predictable and satisfactory outcome that fulfilled the patient's demands. The presented approach overcomes the disadvantages of two-staged implant placement bone grafting procedures and is also a more affordable option for the patient. CBCT evaluation confirmed bone gain with minimal morbidity after the procedure.

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“…Recently, a modified GBR technique called the full‐thickness periosteal envelope technique (FPET) was introduced by the current authors' team (Deng et al., 2022), in which GBR with intact periosteum and deproteinized bovine bone mineral (DBBM) was used to correct the peri‐implant defect. Acceptable results of horizontal bone augmentation were achieved in patients with peri‐implant bone defects.…”

Section: Introductionmentioning

confidence: 99%

Guided bone regeneration for peri‐implant augmentation: A retrospective study comparing two surgical techniques with a mean follow‐up of 26 months

Liu,

Lan,

Gao

et al. 2024

Clinical Oral Implants Res

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ObjectivesTo introduce a modified guided bone regeneration (GBR) technique using intact periosteum and deproteinized bovine bone mineral (DBBM) for peri‐implant augmentation and compare the clinical outcomes with those of conventional GBR.Materials and MethodsPatients who received peri‐implant augmentation in posterior sites between 2015 and 2021 were reviewed in this study. Group A was treated with a modified GBR technique, and Group B was treated with conventional GBR. For group comparison, propensity score matching was performed with a sensitivity analysis. The implant survival rate, dimensional changes in hard tissue, marginal bone loss (MBL), and peri‐implant parameters were evaluated.ResultsIn total, 114 implants from 98 patients were included. The implant survival rates were 95.74% in Group A and 95.00% in Group B during the follow‐up period. At 6 months, the median horizontal thickness was recorded at 0.87 mm (IQ1–IQ3 = 0.00–1.75 mm) in Group A, exhibiting a relatively lower value compared to the corresponding measurement of 0.98 mm (IQ1–IQ3 = 0.00–1.89 mm) in Group B (p = .937). Vertical height displayed no statistically significant intergroup difference between the two groups (p = .758). The mean follow‐up period was 25.83 ± 12.93 months after loading in Group A and 27.47 ± 21.29 months in Group B (p = .761). MBL and peri‐implant parameters were comparable between the two groups.ConclusionsWithin the limitations of this study, the modified GBR technique using intact periosteum and DBBM grafting might be a viable alternative to correct bone defects around implants in molar and premolar sites.

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Using the intact periosteum for horizontal bone augmentation of peri-implant defects: a retrospective cohort study

Cited by 3 publications

References 24 publications

Spp1 secreted by macrophages impairs osteogenic ability of Ctsk⁺Fmod⁺periosteal cells in jaw bone

Spp1 secreted by macrophages impairs osteogenic ability of Ctsk⁺Fmod⁺periosteal cells in jaw bone

A Modified Ridge-Splitting Technique to Restore a Completely Edentulous Maxillary Arch With a Cement-Retained Implant Prosthesis

Guided bone regeneration for peri‐implant augmentation: A retrospective study comparing two surgical techniques with a mean follow‐up of 26 months

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Using the intact periosteum for horizontal bone augmentation of peri-implant defects: a retrospective cohort study

Cited by 3 publications

References 24 publications

Spp1 secreted by macrophages impairs osteogenic ability of Ctsk+Fmod+periosteal cells in jaw bone

Spp1 secreted by macrophages impairs osteogenic ability of Ctsk+Fmod+periosteal cells in jaw bone

A Modified Ridge-Splitting Technique to Restore a Completely Edentulous Maxillary Arch With a Cement-Retained Implant Prosthesis

Guided bone regeneration for peri‐implant augmentation: A retrospective study comparing two surgical techniques with a mean follow‐up of 26 months

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Spp1 secreted by macrophages impairs osteogenic ability of Ctsk⁺Fmod⁺periosteal cells in jaw bone

Spp1 secreted by macrophages impairs osteogenic ability of Ctsk⁺Fmod⁺periosteal cells in jaw bone