One of the most urgent problems of modern metropolises is to ensure environmental safety, since industrial enterprises are concentrated exactly in large cities, which are the main sources of environmental pollution. Despite the fact that environmental problems are receiving more attention from both the state and society, there are no significant positive changes in the environmental condition of the millionaire cities, including Omsk city. The absence of a system of effective interaction of society, government and business in the field of environmental safety is a major factor that has a negative impact on the environmental condition of metropolises. Purpose of research: designing a system of effective interaction between government agencies, business and society in the field of environmental safety to improve the environmental situation in metropolises using cognitive methodology. The study used methods of expert evaluation and cognitive modeling. The main factors influencing the effectiveness of interaction between government agencies, business and society in the field of environmental safety were identified, a corresponding cognitive model was developed and simulation experiments were carried out on its basis, which allowed to predict the degree of influence on target factor and on individual control factors. Based on the simulation results, recommendations for designing a system of effective interaction between government agencies, business and society in the field of environmental safety of metropolises were developed. In the future, using cognitive methodology, it is planned to expand the range of studies of various aspects of environmental problems, considering the specifics of different cities, regions and countries.