Using Ultraviolet C Irradiation as a Sterilization Method for Organ Perfusion Systems

Galasso, M.; Patel, Anjani; Summers, C.S.; Ribeiro, Rejane; Zhang, Y.; Ali, Aiman; Gazzalle, A.; Liu, M.; Keshavjee, S.; Cypel, Marcelo

doi:10.1016/j.healun.2018.01.377

Cited by 3 publications

(1 citation statement)

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“…42 Moving forward, we see potential to expand the donor pool by combining DAA therapies with platforms such as EVLP (to reduce viral loads through the use of ultraviolet C light) for donors with HCV. [41][42][43] Bioengineered Lungs…”

Section: Extended Criteria For Donor Selectionmentioning

confidence: 99%

The Future of Lung Transplantation

Young

Dilling

2019

Chest

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The field of lung transplant has made significant advances over the last several decades. Despite these advances, morbidity and mortality remain high when compared with other solid organ transplants. As the field moves forward, the speed by which progress can be made will in part be determined by our ability to overcome several stumbling blocks, including donor shortage, proper selection of candidates, primary graft dysfunction, and chronic lung allograft dysfunction. The advances and developments surrounding these factors will have a significant impact on shaping the field within the coming years. In this review, we look at the current climate (ripe for expanding the donor pool), new technology (ex vivo lung perfusion and bioengineered lungs), cutting-edge innovation (novel biomarkers and new ways to treat infected donors), and evidence-based medicine to discuss current trends and predict future developments for what we hope is a bright future for the field of lung transplantation.

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