Uterine Lipoleiomyomas

Abstract

Lipoleiomyoma is an uncommon uterine neoplasm and, although presumed to be benign, has been inadequately studied. Confirming the benign nature of this tumor is important because it can closely resemble well-differentiated liposarcoma. We evaluated 50 consecutive lipoleiomyomas diagnosed at the Washington Hospital Center from 1998 to 2004; 2.1% of patients who had uterine leiomyomas during this period had a lipoleiomyoma. The mean and median patient age was 54 and 51 years, respectively. The mean and median tumor size was 4.6 and 2.1 cm, respectively. Forty-three (83%) tumors were located in the uterine corpus, and 7 (13%) were in the cervix. One broad ligament tumor and one retroperitoneal tumor were also studied. The mitotic index was zero for all tumors. No tumors displayed cytological atypia, necrosis, calcification, or other degenerative changes. Follow-up periods ranged from 1.8 to 7.5 years (mean, 5.0 years). Four patients died of unrelated causes. There were no recurrences or fatalities related to tumor. Lipoleiomyoma of the uterus seems to have an uneventful clinical course and can now be confidently regarded as benign.

Broad Ligament Lipoleiomyoma Masses: Two curious cases masquerading as ovarian carcinomas

“…[2][3][4] However, lipoleiomyomas on the broad ligament-a peritoneal fold that connects the uterus to the pelvis-are extremely uncommon, with only seven cases reported in the literature to date. 2,[5][6][7][8][9][10] Broad ligament lipoleiomyomas are difficult to diagnose preoperatively upon radiology and may be mistaken for an ovarian carcinoma. 11 However, it is important to distinguish between these entities as broad ligament lipoleiomyomas can be treated conservatively with a lumpectomy.…”

“…2,3 The most common location of a lipoleiomyoma is the uterus, while other reported sites include the cervix, ovaries and, on occasion, the retroperitoneum. [2][3][4] However, lipoleiomyomas on the broad ligament-a peritoneal fold that connects the uterus to the pelvis-are extremely uncommon, with only seven cases reported in the literature to date.…”

“…[1][2][3] Lipoleiomyomas typically occur in older post-menopausal women, whereas leiomyomas occur mostly in women of reproductive age and usually regress after menopause.…”

“…[1][2][3] Lipoleiomyomas typically occur in older post-menopausal women, whereas leiomyomas occur mostly in women of reproductive age and usually regress after menopause.2,3 The most common location of a lipoleiomyoma is the uterus, while other reported sites include the cervix, ovaries and, on occasion, the retroperitoneum.2-4 However, lipoleiomyomas on the broad ligament-a peritoneal fold that connects the uterus to the pelvis-are extremely uncommon, with only seven cases reported in the literature to date. 2,[5][6][7][8][9][10] Broad ligament lipoleiomyomas are difficult to diagnose preoperatively upon radiology and may be mistaken for an ovarian carcinoma.…”

“…2,[5][6][7][8][9][10] Broad ligament lipoleiomyomas are difficult to diagnose preoperatively upon radiology and may be mistaken for an ovarian carcinoma.…”