Utilidad del CMBD para la detección de acontecimientos adversos por medicamentos

Abstract

3.2% of admissions was caused by ADEs. 2.2% of hospitalized patients experienced ADEs. 62% of ADEs were potentially preventable. A high proportion of preventable ADEs were around a small number of drugs. Effective safety practices directed to reduce the incidence of medication errors are needed.

Adverse drug events in hospitals: a systematic review

“…four 10,11,14,30 did not provide information on the place where they were performed. Interestingly, 62.1% of the studies (18/29) 6,7,8,9,12,13,15,16,19,20,21,22,25,26,27,31,33,34 involved university, academic, or teaching hospitals, i.e., presumably large-scale, high-complexity hospital units.…”

“…The filters consisted basically of rescue drugs, altered laboratory findings, or signs and symptoms related to adverse events. Thirtyeight per cent (11/29) 8,9,13,14,15,17,19,24,30,31,33 of the studies used patient chart review, while in four of these 12,14,30,31 the patient charts were only reviewed to confirm the events. Twenty-eight per cent (8/29) 6,14,21,23,24,25,29,30 of the studies identified the ICD codes related to the events, of which four studies used ICD-9 14,21,23,30 , three ICD-10 6,25,29 , and one the clinically modified ICD-9 24 .…”

“…Forty-eight percent of the studies (14/29) 6,8,9,14,18,19,22,23,24,25,28,29,30,31 used a retrospective approach, i.e., the presence of ADEs was analyzed after the patient was discharged; 48.3% of the studies (14/29) 7,11,12,13,15,16,17,20,21,26,27,32,33,34 used a prospective approach, whereby the ADEs were identified during the hospital stay; and one study 10 was cross-sectional, where ADEs were identified using a survey. Among the studies with a prospective approach, two used retrospective strategies to complement the evaluation, based on an analysis of hospital discharge forms 16,21 .…”

“…Twenty-eight articles remained 6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33 for evaluation, plus one more article retrieved by manual search 34 . Table 1 describes the studies, conducted in 13 countries from North America, Europe, South America, and Asia.…”

“…Only 41.4% (12/29) 6,7,10,11,12,20,21,26,27,28,29,33 provided information about age, and 24.1% (7/29) 6,7,10,20,26,27,33 on gender. As for the unit of analysis, 62.1% (18/29) 6,7,10,11,12,15,18,20,21,24,25,26,27,30,31,32,33,34 used the number of patients or patient charts, 48.3% (14/29) 6,8,9,12,14,16,17,20,22,23,25,28,29,33 the number of admissions or discharges, and 24.1% (7/29) 13,16,17,19,31,…”