Utility of baseline impedance level measurement in patients with gastroesophageal reflux symptoms

Kim, Ban-Suk; Park, Seon-Young; Lee, Du-Hyun; Cho, Eunae; Jun, Chung‐Hwan; Park, Chang-Hwan; Kim, Hyunsoo; Choi, Sung‐Kyu; Rew, Jong Sun

doi:10.3109/00365521.2015.1042031

Cited by 8 publications

(7 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…[10,29] In our study, we found that there was a decreasing tendency in BILs from proximal esophagus to distal esophagus in RGERD patients and patients with acid reflux type. But the lowest distal BILs of RGERD patients were nearly 2 thousands of Ohms, which were higher than those from above-mentioned studies.…”

Section: Discussionmentioning

confidence: 66%

“…[9–11,29,30] Overall, it is reasonable to hypothesize that BILs decrease in parallel with the severity of GERD, from healthy to NERD, and then RE. Consistent with above studies, our data revealed that patients with severe esophagitis had lower distal BILs than those with mild esophagitis and NERD, and that patients with severe esophagitis in acid reflux type had lowest distal BILs.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Role of altered esophageal intraluminal baseline impedance levels in patients with gatroesophageal reflux disease refractory to proton pump inhibitors

Jiang

Ye²,

Lin³

et al. 2016

Medicine

View full text Add to dashboard Cite

Numerous studies have investigated utility of esophageal intraluminal baseline impedance levels (BILs) in gastroesophageal reflux disease (GERD). However, effect of BILs in refractory GERD (RGERD) has not been well investigated. The aim of this study is to evaluate role of BILs in RGERD patients. Total 62 subjects with refractory gastroesophageal reflux symptoms underwent 24-hour impedance-pH monitoring and gastroendoscopy. Distal BILs in acid reflux type were significantly lower than those in nonacid reflux type and functional heartburn (FH) group. Distal BILs of reflux esophagitis (RE) patients were lower than those of nonerosive reflux disease (NERD) patients, while there were no statistical significance between 2 groups. Patients with severe esophagitis had lower distal BILs than those with mild esophagitis and NERD patients, and patients with severe esophagitis in acid reflux type had the lowest distal BILs. Distal BILs were significantly negatively correlated with DeMeester score, episodes of acid reflux, and acid exposure time, but no correlated with episodes of nonacid reflux. Characteristics of BILs in RGERD patients were similar with those in GERD patients, but might be more complicated. Evaluating BILs in RGERD patients could achieve a better understanding of pathophysiology in RGERD.

show abstract

Section: Discussionmentioning

confidence: 66%

Section: Discussionmentioning

confidence: 99%

Role of altered esophageal intraluminal baseline impedance levels in patients with gatroesophageal reflux disease refractory to proton pump inhibitors

Jiang

Ye²,

Lin³

et al. 2016

Medicine

View full text Add to dashboard Cite

show abstract

“…Saritas Yuksel et al found that impedance values were similar at 10 cm above the LES for both GERD patients and healthy controls 28 . Consistently, the distal, but not the proximal BI values, were found to be lower in patients with reflux in a recent study 31 . These results could be interpreted as evidence that chronic exposure of the esophageal mucosa is less in the proximal esophagus in typical GERD patients.…”

Section: Discussionmentioning

confidence: 82%

“…28 Consistently, the distal, but not the proximal BI values, were found to be lower in patients with reflux in a recent study. 31 These results could be interpreted as evidence that chronic exposure of the esophageal mucosa is less in the proximal esophagus in typical GERD patients. In our study, we found that the proximal BI in patients with LPR symptoms was lower than in patients with typical symptoms without differences in their AET values.…”

Section: Discussionmentioning

confidence: 85%

The diagnostic value of 24‐hour ambulatory intraesophageal pH‐impedance in patients with laryngopharyngeal reflux symptoms comparable with typical symptoms

et al. 2017

View full text Add to dashboard Cite

Patients with pathologic laryngopharyngeal reflux symptom scores had lower proximal baseline impedance levels and lower proximal-to-distal ratios, which may reflect the proximal mucosal noxious effect of the refluxate. These results may indicate that laryngopharyngeal reflux symptoms may be due to chronic acid exposure in the proximal segments of the esophagus, and the proximal-to-distal ratio may be used as a new metric for diagnosis.

show abstract

“…In 2016, an IHC study collected the clinicopathological information of 28 patients received surgical resection for pancreatic cancer to determine the value of NLR as a prognostic factor in patients with pancreatic cancer. [ 23 ] Researchers found iNLR ≥ 5 was an important risk factor of poor disease-free survival and OS. Nevertheless, few studies focusing on iNLR in ESCC are available.…”

Section: Discussionmentioning

confidence: 99%

Prognostic value of neutrophil-to-lymphocyte ratio in peripheral blood and pathological tissue in patients with esophageal squamous cell carcinoma

Guo

Shao

et al. 2020

Medicine

View full text Add to dashboard Cite

The aim of this study was to investigate the prognostic value of neutrophils-to-lymphocyte ratio in peripheral blood (NLR) and in cancer nest (iNLR) in patients with esophageal squamous cell carcinoma (ESCC). Totally 103 patients with ESCC treated with surgical radical surgery in the Shuyang People's Hospital from February 2010 to November 2014 were collected retrospectively. Peripheral blood routine test and immunohistochemistry examination of carcinoma nest were mainly performed. Survival rates were analyzed with Kaplan–Meier curves. Univariate analysis and multivariate analysis were also performed to explore potential prognostic factors of ESCC. The median survival time after surgery of low NLR group and high NLR group were 48 months and 30 months, respectively. The difference of overall survival between the 2 groups was statistically significant ( χ 2 = 7.435, P = .006). The median survival time after surgery of low iNLR group and high iNLR group were 37 months and 24.5 months, respectively. The difference between the 2 groups was also statistically significant ( χ 2 = 33.640, P = .000). Univariate analysis showed influence factors of postoperative survival in patients with ESCC included tumor-node-metastasis staging, NLR, iNLR, and grade of NLR score + iNLR score ( P ≤ .05). Multivariate analysis confirmed NLR, iNLR, and tumor-node-metastasis staging were independent influence factors of postoperative survival in patients with ESCC ( P ≤ .05). High level of NLR and iNLR implies a poor prognosis of ESCC. The application of both NLR and iNLR could guide clinicians to take aggressive treatments for high risk population.

show abstract

Utility of baseline impedance level measurement in patients with gastroesophageal reflux symptoms

Abstract: BILs are related to GER, especially acid reflux. Location and duration of assessment for BILs needs to be standardized. Six-hour BILs could be substitutes for 24-h BILs. During analysis of MII-pH, more attention should be paid to BILs in the lower esophagus.

Cited by 8 publications

References 14 publications

Role of altered esophageal intraluminal baseline impedance levels in patients with gatroesophageal reflux disease refractory to proton pump inhibitors

Role of altered esophageal intraluminal baseline impedance levels in patients with gatroesophageal reflux disease refractory to proton pump inhibitors

The diagnostic value of 24‐hour ambulatory intraesophageal pH‐impedance in patients with laryngopharyngeal reflux symptoms comparable with typical symptoms

Prognostic value of neutrophil-to-lymphocyte ratio in peripheral blood and pathological tissue in patients with esophageal squamous cell carcinoma

Contact Info

Product

Resources

About