Utility of evaluating semen samples from adolescents with Klinefelter Syndrome for cryopreservation: A multi-institution evaluation

Counseling for the man with severe male infertility

“…Only 8.3% of patients had rare sperm in their ejaculate, the remainder of participants were azoospermic. Patients who repeated a semen analysis did not demonstrate better retrieval results, suggesting that one semen analysis is sufficient for attempts at cryopreservation [9]. Microscopic testicular sperm extraction (mTESE) in Klinefelter syndrome patients is often performed in men found to be azoospermic, and predictors for positive retrieval and conception outcomes have been recently investigated.…”