Utility of multi‐frequency bioelectrical impedance compared to deuterium dilution for assessment of total body water

Abstract

Aim Multi‐frequency bioelectrical impedance analysis (MF‐BIA) may provide a quick, cost‐efficient method of total body water (TBW) assessment. We compared TBW estimates from the Biospace InBody 520, 720, and S10 MF‐BIA devices to TBW estimates from isotopic deuterium dilution (D2O). Methods TBW was measured in 25 men and 25 women, 18–49 years, 73.6 ± 15.4 kg on each of the three devices and from D2O analysis. Results All MF‐BIA devices significantly overestimated TBW compared to D2O TBW for men (4.7–5.4 kg, 10.8–12.4%; P < 0.01) and women (3.7–4.3 kg, 12.3–14.3%; P < 0.01). Regression analyses in men revealed R2 (0.86–0.90) and SEE (1.7–2.0 kg), and in women revealed R2 (0.82–0.86) and SEE (1.5–1.6 kg). Bland and Altman analyses revealed similar limits of agreement for men (3.5–3.9 kg) and women (3.4–3.7 kg). Conclusions The Biospace InBody devices significantly overestimate TBW in men and women. The consistent bias for men and the increasing bias with increasing TBW for women may indicate that these devices are suitable for group TBW estimates in men only.

Reliability and validity of various laboratory methods of body composition assessment in young adults

“…Finally, recent work from Nickerson et al has indicated that predicting RV may have a smaller SEM than UWW when incorporated into a four-compartment model, but that individual error may preclude its use as a criterion measure (Nickerson et al, 2017b). A final limitation is that the InBody device may overestimate TBW when compared to isotopic dilution (4Á1-5Á4 kg) or bioimpedance spectroscopy devices (Anderson et al, 2015); these authors also showed very high agreement (>0Á99 ICC; 0Á5-1Á1% CV) between isotopic dilution and InBody TBW, with a typical error of 1Á2-1Á3 kgs (Anderson et al, 2015). However, it is worth nothing that the authors…”

Exploration of Fluid Dynamics in Perioperative Patients Using Bioimpedance Analysis

“…21 Validity and reliability of BIA have been tested extensively in other studies. [17][18][19] Results from these studies have shown coefficient of determination (r 2 ) ranging between 0.81 and 0.90. Although the results were validated in healthy individuals, validity in surgical patients may be shortcoming.…”

“…The BIA protocol used for this study were also described and validated in other studies. [17][18][19] Statistical Analysis…”

Nutrition‐related factors associated with waiting list mortality in patients with interstitial lung disease: A retrospective cohort study

“…[17][18][19] Soft lean mass, which comprises mostly muscle mass (cardiac, smooth, and skeletal muscle), was calculated by excluding the mineral found in the bones from fat free mass. TTR and body composition were routinely measured by turbidimetric immunoassay (Nittobo Medical) and multifrequency bioelectrical impedance methods (InBody ® 720, InBody Japan, Inc), respectively, at admission.…”

“…The impedance method estimates %soft lean mass and %fat mass of the five body segments (right arm, left arm, trunk, right leg, and left leg) based on 30 impedance determinations at six different frequencies through tetrapolar eight-point tactile electrodes. [17][18][19] Soft lean mass, which comprises mostly muscle mass (cardiac, smooth, and skeletal muscle), was calculated by excluding the mineral found in the bones from fat free mass. Finally, muscle mass of trunk and skeletal muscle mass of whole body, arms, and legs were estimated using the manufacturer's software (Lookin'Body 120); the range from 90% to 110% of the standard skeletal muscle mass was considered as the normal skeletal muscle mass, the range <90% of the standard was considered low, and the range over 110% was considered high.…”