UV-C light completely blocks highly contagious Delta SARS-CoV-2 aerosol transmission in hamsters

Fischer, Robert J.; Port, Julia R; Holbrook, Myndi G.; Yinda, Kwe Claude; Creusen, Martin; Stege, Jeroen ter; Samber, Marc de; Munster, Vincent J.

doi:10.1101/2022.01.10.475722

Cited by 1 publication

(2 citation statements)

References 16 publications

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“… 116 Using an animal model system, aerosol transmission could be interrupted with UV‐C. 117 Other measures of virus aerosol inactivation confirm the latter. 112 …”

Section: Irradiation Methodsmentioning

confidence: 91%

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Disinfection and decontamination in the context of SARS‐CoV‐2‐specific data

Cimolai

2022

Journal of Medical Virology

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Given the high transmissibility of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) as witnessed early in the coronavirus disease 2019 (COVID‐19) pandemic, concerns arose with the existing methods for virus disinfection and decontamination. The need for SARS‐CoV‐2‐specific data stimulated considerable research in this regard. Overall, SARS‐CoV‐2 is practically and equally susceptible to approaches for disinfection and decontamination that have been previously found for other human or animal coronaviruses. The latter have included techniques utilizing temperature modulation, pH extremes, irradiation, and chemical treatments. These physicochemical methods are a necessary adjunct to other prevention strategies, given the environmental and patient surface ubiquity of the virus. Classic studies of disinfection have also allowed for extrapolation to the eradication of the virus on human mucosal surfaces by some chemical means. Despite considerable laboratory study, practical field assessments are generally lacking and need to be encouraged to confirm the correlation of interventions with viral eradication and infection prevention. Transparency in the constitution and use of any method or chemical is also essential to furthering practical applications.

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“… 116 Using an animal model system, aerosol transmission could be interrupted with UV‐C. 117 Other measures of virus aerosol inactivation confirm the latter. 112 …”

Section: Irradiation Methodsmentioning

confidence: 91%

“…The mechanism of action of UV‐C was more correlated with viral RNA effects than those on structural protein changes 116 . Using an animal model system, aerosol transmission could be interrupted with UV‐C 117 . Other measures of virus aerosol inactivation confirm the latter 112 …”

Section: Irradiation Methodsmentioning

confidence: 93%

Disinfection and decontamination in the context of SARS‐CoV‐2‐specific data

Cimolai

2022

Journal of Medical Virology

View full text Add to dashboard Cite

show abstract

UV-C light completely blocks highly contagious Delta SARS-CoV-2 aerosol transmission in hamsters

Cited by 1 publication

References 16 publications

Disinfection and decontamination in the context of SARS‐CoV‐2‐specific data

Disinfection and decontamination in the context of SARS‐CoV‐2‐specific data

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