Vaginal Metastasis as the First Sign of Renal Cell Carcinoma

Ovesen, Henrik; Gerstenberg, Th.

doi:10.3109/00365599009180868

Cited by 21 publications

(4 citation statements)

References 11 publications

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“…RCC has been demonstrated to metastasize to practically all soft tissues of the body including the tongue, thyroid, eye, gallbladder, pancreas, heart, bladder, vagina, penis, and most peripheral and axial skeletal muscles [10,15,16,[33][34][35]. As a result, generalized evidence of metastatic recurrence should be sought in follow-up protocols.…”

Section: Sites Of Tumor Recurrencementioning

confidence: 99%

Surveillance following radical or partial nephrectomy for renal cell carcinoma

Lam¹,

Leppert²,

Figlin³

et al. 2005

Curr Urol Rep

103

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Renal cell carcinoma (RCC) is the most lethal of the common urologic malignancies, with approximately 40% of patients eventually dying of cancer progression. Approximately one third of patients present with metastatic disease and up to 50% treated for localized disease have a recurrence. Although the prognosis generally is poor in these patients, some may respond to immunotherapy and a subset of patients who develop solitary metastases can achieve long-term survival. Therefore, the timely identification of recurrences following surgical extirpation is imperative in the treatment of patients.

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Section: Sites Of Tumor Recurrencementioning

confidence: 99%

Surveillance following radical or partial nephrectomy for renal cell carcinoma

Lam¹,

Leppert²,

Figlin³

et al. 2005

Curr Urol Rep

103

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show abstract

“…Tumor emboli then dissipate to the vagina via venous reflux of the ovarian vein. The proposed mechanism may then explain the increased prevalence of vaginal metastases in tumors of the left kidney, as observed in the present patient [ 9 ]. Right-sided RCC also have the potential to cause vaginal metastases in patients.…”

Section: Discussionmentioning

confidence: 83%

Vaginal Bleeding as Initial Presentation of an Aggressive Renal Cell Carcinoma: A Case Report and Review of the Literature

Jimenez

Rolon

Eyzaguirre

et al. 2018

Case Reports in Pathology

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Introduction Renal cell carcinoma is the third most common urogenital cancer. In some patients, it can metastasize to distant organs. Metastasis to the vagina is extremely rare. Case Presentation A 54-year-old female with unremarkable history presented to the clinic with a chief complaint of vaginal bleeding. Further examination identified a pedunculated mass on the vaginal wall. Histologic examination revealed a metastatic clear cell renal cell carcinoma. Radiological studies then revealed a left renal mass and bilateral adrenal masses. The patient underwent a nephrectomy, adrenalectomy, and resection of the vaginal mass. The mass in the vagina has since recurred. ConclusionWe report the first known case of vaginal metastasis as initial presentation of a renal cell carcinoma with rhabdoid features. Postmenopausal women with renal cell carcinoma who present with vaginal bleeding should undergo a thorough inspection of the vaginal wall for the potential of metastatic neoplasms.

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“…The existence of a renal vein thrombus (left) or inferior vena cava (right), promote the spin-cell tumor in the spermatic vein reflux, as well as the occurrence of varicocele. [6]. Time between metastasis and primary tumor varies different depending on the type of organ affected.…”

Section: Discussionmentioning

confidence: 99%

Sciatica leading to the discovery of a renal cell carcinoma

Lakmichi¹,

Jarir²,

Kabour³

et al. 2011

Pan Afr Med Jrnl

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Metastatic renal cell cancer is not exceptional in kidney cancer (30% of patients with kidneyl cancer). Its prognosis is particularly severe. However, sciatic neuralgia (sciatica) remains an exceptional revealing clinical sign of this disease. The authors report the case of a patient admitted with right sciatica as chief complain, leading to the discovery of a renal cell carcinoma. Although uncommon, renal cell carcinoma spine metastasis should be included in the differential diagnosis of back pain and sciatica.

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Vaginal Metastasis as the First Sign of Renal Cell Carcinoma

Cited by 21 publications

References 11 publications

Surveillance following radical or partial nephrectomy for renal cell carcinoma

Surveillance following radical or partial nephrectomy for renal cell carcinoma

Vaginal Bleeding as Initial Presentation of an Aggressive Renal Cell Carcinoma: A Case Report and Review of the Literature

Sciatica leading to the discovery of a renal cell carcinoma

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