Validation and comparison of five preference-based measures among age-related macular degeneration patients: evidence from mainland China

Shen, Yingzhong; Li, Shunping; Xu, Yanjiao; Chen, Gang

doi:10.1007/s11136-021-03047-1

Cited by 7 publications

(5 citation statements)

References 54 publications

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“…The choice of health utility measures for the calculation of QALYs depends on many aspects, including but not limited to the psychometric properties of the measures, brevity and ease of use, the availability of country-specific tariff and the comparability across different diseases [ 51 ]. From an economics perspective, the SG and TTO are the most accepted approaches because they are based implicitly on utility theory and involve an inherent gamble or trade-off [ 52 ].…”

Section: Discussionmentioning

confidence: 99%

Psychometric properties and comparison of four health utility approaches among myopia patients in China

Dou

Chen

et al. 2023

Health Qual Life Outcomes

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Background The increased prevalence of myopia creates and earlier age of onset has created public health concerns for the long-term eye health, vision impairment and carries with it a significant economic burden. The quality of the economic evaluation is dependent on the sensitivity and validity of the approaches. Nowadays, there are many approaches to measure patients’ health state utility (HSU). However, little is known regarding the performance of direct approach and indirect approach in people with myopia. This study is aimed to compare the psychometric properties of four HSU approaches among patients with myopia in mainland China, including two direct approaches (TTO and SG), the generic preference-based measures (PBM) (AQoL-7D) and the disease-specific PBM (VFQ-UI). Methods A convenience sampling framework was used to recruit patients with myopia who attended a large ophthalmic hospital in Jinan, China. Spearman’s rank correlations coefficient was used to assess concurrent validity. Known-group validity was analyzed by: (1) whether the patients wear corrective devices; (2) severity of myopia as low or moderate to high of the better eye; (3) duration of myopia as ≤ 10 years or > 10 years. Effect size (ES), relative efficiency (RE) statistic and the largest area under the receiver operating characteristic curve (AUC) were used to assess sensitivity. The intra-class correlation coefficient (ICC) and Bland–Altman plots were used to assess agreement. Results A valid sample size of 477 myopia patients was analyzed (median duration: 10 years). The mean HSU scores between TTO and SG were similar (0.95) and higher than AQoL-7D (0.89) and VFQ-UI (0.83). Overall, the VFQ-UI had the best performance based on the psychometric analysis. The agreement indicated that there was no pair of approaches that could be used interchangeably. Conclusions The VFQ-UI showed better psychometric properties than other three approaches for providing health state utility in Chinese myopia patients. Given the widespread use and its generic nature of the AQoL-7D, it could be used alongside with VFQ-UI to provide complementary health state utility from a generic and disease-specific perspective for economic evaluation. More evidence on the responsiveness of four health utility approaches in myopia patients is required.

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Section: Discussionmentioning

confidence: 99%

Psychometric properties and comparison of four health utility approaches among myopia patients in China

Dou

Chen

et al. 2023

Health Qual Life Outcomes

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“…Ensuring that these tools are culturally relevant and sensitive to the population's characteristics is crucial for obtaining meaningful and applicable results in economic evaluations. Moreover, it's essential to transparently report the methods used to derive utility scores or QALYs from these instruments, as this can significantly impact the results and their applicability in healthcare decision-making [ 36 ].…”

Section: Methodsmentioning

confidence: 99%

Economic evaluation of dialysis and comprehensive conservative care for chronic kidney disease using the ICECAP-O and EQ-5D-5L; a comparison of evaluation instruments

Zahirian Moghadam,

Powell,

Sharghi

et al. 2023

Cost Eff Resour Alloc

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Background Chronic Kidney Disease (CKD) patients often require long-term care, and while Hemodialysis (HD) is the standard treatment, Comprehensive Conservative Care (CCC) is gaining popularity as an alternative. Economic evaluations comparing their cost-effectiveness are crucial. This study aims to perform a cost-utility analysis comparing HD and CCC using the EQ-5D-5L and ICECAP-O instruments to assessing healthcare interventions in CKD patients. Methods This short-term economic evaluation involved 183 participants (105 HD, 76 CCC) and collected data on demographics, comorbidities, laboratory results, treatment costs, and HRQoL measured by ICECAP-O and EQ-5D-5L. Incremental Cost-Effectiveness Ratios (ICERs) and Net Monetary Benefit (NMB) were calculated separately for each instrument, and Probabilistic Sensitivity Analysis (PSA) assessed uncertainty. Results CCC demonstrated significantly lower costs (mean difference $8,544.52) compared to HD. Both EQ-5D-5L and ICECAP-O indicated higher Quality-Adjusted Life Years (QALYs) for both groups, but the difference was not statistically significant (p > 0.05). CCC dominated HD in terms of HRQoL measures, with ICERs of -$141,742.67 (EQ-5D-5L) and -$4,272.26 (ICECAP-O). NMB was positive for CCC and negative for HD, highlighting its economic feasibility. Conclusion CCC proves a preferable and more cost-effective treatment option than HD for CKD patients aged 65 and above, regardless of the quality-of-life measure used for QALY calculations. Both EQ-5D-5L and ICECAP-O showed similar results in cost-utility analysis.

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“…Well-designed well-being measures are useful to rationalize resource allocation in health and social care in China, however, limited well-being measures are available for use in Chinese populations. The ICECAP-A (ICEpop CAPability measure for adults) was adapted in Chinese 16 , but was found to perform less satisfactorily compared to EQ-5D and AQoL-7D 17 , 18 and has not been frequently used in practice in China. The Short Warwick–Edinburgh Mental Well-Being Scale (SWEMWS) has been translated into Chinese and has been demonstrated in the general population and hospitalized patients 19 , 20 , but it focuses more on positive mental well-being and does not aim to estimate utilities.…”

Section: Introductionmentioning

confidence: 99%

A head-to-head comparison of well-being of older people (WOOP) and EQ-5D-5L in patients, carers and general public in China

Ran

Mao

Yang

2023

Sci Rep

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Recently, well-being of older people measure (WOOP) was developed and validated in a Dutch population. Although WOOP was developed targeting the older people, it has the potential for use in a wider population. In this study, we aimed to examine the relationship between WOOP and EQ-5D-5L and compared their psychometric properties in a sample of patients, carers and healthy general public covering a wider age group. We conducted a cross-sectional study in Guizhou Province, China between July and August 2022. Data was collected using paper and pencil. We analysed and reported the acceptability, item response distribution, the Spearman correlation coefficients of all items, the Exploratory Factor Analysis (EFA) of all items, the known-group validity and the convergent validity of EQ-5D-5L utility and WOOP utility. A total of 322 participants completed the survey with 105 patients, 101 carers and 116 healthy general public. 9% of participants had at least one missing response. Three items of WOOP did not have any level 5 responses and EQ-5D-5L had more level 1 responses. The correlations were low between EQ-5D-5L and WOOP items and the three-factor EFA showed these two instruments had only one shared factor and the other two factors were only related to WOOP items. Younger people had lower missing response rate and a different response distribution for three items. WOOP measures a broader construct beyond health while EQ-5D-5L is a more sensitive instrument when health is considered alone. There is a potential of using WOOP in a wider population.

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Validation and comparison of five preference-based measures among age-related macular degeneration patients: evidence from mainland China

Cited by 7 publications

References 54 publications

Psychometric properties and comparison of four health utility approaches among myopia patients in China

Psychometric properties and comparison of four health utility approaches among myopia patients in China

Economic evaluation of dialysis and comprehensive conservative care for chronic kidney disease using the ICECAP-O and EQ-5D-5L; a comparison of evaluation instruments

A head-to-head comparison of well-being of older people (WOOP) and EQ-5D-5L in patients, carers and general public in China

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