Validation of a Graded Response Questionnaire for the Diagnosis of Gastroesophageal Reflux Disease in an Asian Primary Care Population

Ho, Khek Yu; Gwee, Kok‐Ann; Khor, Jen Lock; Selamat, Dede Sutedja; Yeoh, Khay Guan

doi:10.1097/mcg.0b013e3180653613

Cited by 24 publications

(16 citation statements)

References 12 publications

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“…In addition, the symptom of heartburn cannot reliably diff erentiate GER from another highly prevalent disorder of the upper gastrointestinal tract, dyspepsia ( 10,12,13,25 ). Upper a pH study ( 14 -16 ), while still others have limited sensitivity and specifi city ( 11,18,19 ). In addition, most questionnaires have not yet been routinely used outside of the research arena.…”

Section: Discussionmentioning

confidence: 99%

A Prospective Study to Compare a Symptom-Based Reflux Disease Questionnaire to 48-h Wireless pH Monitoring for the Identification of Gastroesophageal Reflux (revised 2-26-11)

Lacy

Chehade

Crowell

2011

American Journal of Gastroenterology

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Section: Discussionmentioning

confidence: 99%

A Prospective Study to Compare a Symptom-Based Reflux Disease Questionnaire to 48-h Wireless pH Monitoring for the Identification of Gastroesophageal Reflux (revised 2-26-11)

Lacy

Chehade

Crowell

2011

American Journal of Gastroenterology

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“…In a population study carried out in Asia, the authors detected 20.2% of epigastric pain and only 2.1% of heartburn (20) . The varia tion observed in different countries can suggest a difference in the gastrointestinal symptom development pattern between the Eastern and Western populations and different diagnosis instruments used.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of dyspeptic symptoms and heartburn of adults in Belo Horizonte, Brazil

Almeida

Martins

Cunha

et al. 2017

Arq. Gastroenterol.

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-Background -Medical literature has shown dyspepsia and heartburn related symptoms occur among 15% to 40% of the population. These symptoms can occur at any age and are more prevalent in women. Objective -Investigate the prevalence of dyspeptic symptoms and heartburn among individuals over 18. Methods -Individuals over 18 were randomly selected in public venues in Belo Horizonte/MG to participate. A standardized questionnaire that included questions related to social demographic characteristics, eating habits, digestive symptoms, medical appointments, medi cations, exams, previous surgeries and comorbidities was applied. A questionnaire about functional dyspepsia diagnosis (Rome III) was also applied.Results -A total of 548 individuals were interviewed. Among these, 58.4% were women, 59.3% were white, 55.9% were single and the average age was 36 years. Within this group, 376 individuals (68.6%) declared to have some symptom and/or use medication to relieve dyspepsia symptoms, and for these patients were applied the Rome III questionnaire. Based on the diagnostic criteria for the questionnaire proposed by the Rome III consensus, the symptom of postprandial fullness was reported by 6.7% of the individuals, early satiety (3.5%) and epigastric pain (10.6%). The overlap of these symptoms was very frequent. The prevalence of functional dyspepsia was 10.6% (postprandial discomfort syndrome (8.2%) and epigastric pain syndrome (2.4%). Among all participants, 52.5% reported heartburn, and 11.1% presented this symptom at least once a week. The most used drug was omeprazole. Conclusion -The prevalence of dyspeptic symptoms and heartburn among a Brazilian adult urban population is similar to those described in other countries. HEADINGS -Dyspepsia, diagnosis. Heartburn. Consenso.

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“…Furthermore, global consensus-based definitions of FGIDs and GERD were used, and reliability and validation of Chinese version of ESS were confirmed. 6,22,46 However, this study was a cross-sectional study and these types of studies are insufficient in establishing cause-effect relationships. Also, the prevalence of EDS found in this study might be overestimated because the ESS is a subjective measuring method.…”

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confidence: 99%

Association Between Excessive Daytime Sleepiness and Functional Gastrointestinal Disorders: A Population-based Study in China

Chen

Zhao

et al. 2017

J Neurogastroenterol Motil

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Background/AimsSeveral studies have demonstrated that sleep problems are associated with functional gastrointestinal disorders (FGIDs): irritable bowel syndrome (IBS), functional dyspepsia, etc, but the relationship between excessive daytime sleepiness (EDS) and FGIDs has not been systematically studied in the general population. This study aims to explore the relationship between EDS and specific types of FGIDs and the effect of the number of FGIDs on EDS. MethodsA sample of 3600 individuals (aged 18-80 years) was selected from 5 regions in China using a randomized, stratified, multi-stage sampling method. EDS was measured by the Epworth Sleepiness Scale, while gastroesophageal reflux disease (GERD) and other FGIDs were assessed by Reflux Disease Questionnaire and the Rome II diagnostic criteria, respectively. ResultsThe survey was completed by 2906 individuals (response rate: 80.72%), and 644 individuals (22.16%) had EDS. EDS was significantly associated with ulcer-like dyspepsia (OR, 2.50; 95% CI, 1.08-5.79), diarrhea-predominant IBS (OR, 2.00; 95% CI, 1.09-3.66), alternating IBS (OR, 2.32; 95% CI, 1.30-4.13), functional constipation (OR, 1.68; 95% CI, 1.20-2.35), and GERD (OR, 1.72; 95% CI, 1.08-2.72). Risk of EDS increased along with the increasing numbers of FGIDs: with 1 FGID (OR, 1.72; 95% CI, 1.37-2.15); with 2 FGIDs (OR, 2.43; 95% CI, 1.63-3.62); and with 3 or more FGIDs (OR, 3.26; 95% CI,). ConclusionsFGIDs, such as ulcer-like dyspepsia, diarrhea-predominant IBS, alternating IBS, functional constipation, and GERD, were significantly associated with EDS. Those who suffered from more kinds of FGIDs were more susceptible to EDS.

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Validation of a Graded Response Questionnaire for the Diagnosis of Gastroesophageal Reflux Disease in an Asian Primary Care Population

Abstract: The questionnaires demonstrated good construct reliability, which were highly sensitive and reasonably specific for the detection of GERD. They are useful tools to help primary care physicians in identifying GERD in patients presenting with uninvestigated upper abdominal symptoms.

Cited by 24 publications

References 12 publications

A Prospective Study to Compare a Symptom-Based Reflux Disease Questionnaire to 48-h Wireless pH Monitoring for the Identification of Gastroesophageal Reflux (revised 2-26-11)

A Prospective Study to Compare a Symptom-Based Reflux Disease Questionnaire to 48-h Wireless pH Monitoring for the Identification of Gastroesophageal Reflux (revised 2-26-11)

Prevalence of dyspeptic symptoms and heartburn of adults in Belo Horizonte, Brazil

Association Between Excessive Daytime Sleepiness and Functional Gastrointestinal Disorders: A Population-based Study in China

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