Validation of a mail questionnaire for parkinsonism in two languages (German and Italian)

Pramstaller, Peter P.; Falk, Markus; Schoenhuber, R; Poewe, Werner

doi:10.1007/s004150050312

Cited by 30 publications

(33 citation statements)

References 9 publications

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“…Some people may not want to admit to their health problems, others are too busy with their daily tasks securing survival to realize that they have signs or symptoms of a slowly progressive disorder. Another reason for the low prevalence of PD may be a low sensitivity of the screening questionnaire, although it had been tested in Caucasians with good results [7,23]. Transferral into a different cultural context may be difficult.…”

Section: Discussionmentioning

confidence: 99%

“…All those aged \50 years with a positive screening through the head of household were also re-interviewed directly. The screening questions, as shown in the Appendix, were asked consecutively [7,23]. Interviewers were allowed to stray from the original question and explain in more detail if the question was not understood.…”

Section: Survey and Operational Instrumentsmentioning

confidence: 99%

“…The screening questions were based on two previously conducted epidemiological studies and were reported with high sensitivity and specificity [7,23]. People who were screen-positive for PD were examined by a specialist neurologist (ASW), who performed an in-depth interview with a questionnaire specific for PD, including a physical examination.…”

Section: Diagnostic Criteriamentioning

confidence: 99%

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Parkinsonism in a population of northern Tanzania: a community-based door-to-door study in combination with a prospective hospital-based evaluation

et al. 2009

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The prevalence of Parkinson's disease (PD) in sub-Saharan Africa is still a matter of debate. The few studies that have been conducted have shown prevalences lower than those in the western world. Whether this represents a genuine finding is unclear to date. In northern Tanzania, we have conducted a hospital-based evaluation and a community-based door-to-door study to assess the prevalence of Parkinsonism, including that of PD. Over a period of 8 months, all patients admitted to a mid-size rural hospital were screened for PD. In parallel, 1,569 people aged >or=50 years were recruited from the communities and assessed for PD with standard questions. Sampling was performed according to the method of "multistage cluster sampling." The questions had previously been tested in a pilot study prior to the survey. People who screened positive were examined by a specialist neurologist. In the hospital, eight of 740 people with neurological diagnoses had Parkinsonism, of whom three patients had a diagnosis of PD. In the community-based study, 18 people answered positively to least one of the 12 screening questions. However, the diagnosis of PD could not be confirmed by further examination in any of them. The prevalence of PD in northern Tanzania was found to be very low. This result would need confirmation in studies with larger populations, ideally of different African ethnicities.

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Section: Discussionmentioning

confidence: 99%

Section: Survey and Operational Instrumentsmentioning

confidence: 99%

Section: Diagnostic Criteriamentioning

confidence: 99%

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Parkinsonism in a population of northern Tanzania: a community-based door-to-door study in combination with a prospective hospital-based evaluation

et al. 2009

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“…24 Self-reported change in motor symptoms was captured using a nine-item parkinsonism questionnaire. 25,[26][27][28] Epidemiological risk factors previously associated with PD were assessed with single-item questions. Caffeine consumption was defined as intake of all types of caffeine-containing beverages (e.g., tea, coffee, cola, and Mellow Yellow).…”

Section: Assessmentsmentioning

confidence: 99%

Impaired olfaction and other prodromal features in the Parkinson At‐Risk Syndrome study

Siderowf¹,

Jennings²,

Eberly³

et al. 2012

Movement Disorders

170

160

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To test the association between impaired olfaction and other prodromal features of PD in the Parkinson At-Risk Syndrome Study. The onset of olfactory dysfunction in PD typically precedes motor features, suggesting that olfactory testing could be used as a screening test. A combined strategy that uses other prodromal nonmotor features, along with olfactory testing, may be more efficient than hyposmia alone for detecting the risk of PD. Individuals with no neurological diagnosis completed a mail survey, including the 40-item University of Pennsylvania Smell Identification Test, and questions on prodromal features of PD. The frequency of reported nonmotor features was compared across individuals with and without hyposmia. A total of 4,999 subjects completed and returned the survey and smell test. Of these, 669 were at or below the 15th percentile based on age and gender, indicating hyposmia. Hyposmics were significantly more likely to endorse nonmotor features, including anxiety and depression, constipation, and rapid eye movement sleep behavior disorder symptoms, and to report changes in motor function. Twenty-six percent of subjects with combinations of four or more nonmotor features were hyposmic, compared to 12% for those reporting three or fewer nonmotor features (P < 0.0001). Hyposmia is associated with other nonmotor features of PD in undiagnosed individuals. Further assessment of hyposmic subjects using more specific markers for degeneration, such as dopamine transporter imaging, will evaluate whether combining hyposmia and other nonmotor features is useful in assessing the risk of future neurodegeneration.

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“…The first algorithm, referred to as the parkinsonian algorithm, was designed to map on to diagnostic criteria for PD based on results from previous validation studies of screening questions [5,[20][21][22]26]. Twins were considered positive if they endorsed shaking arms or legs plus one of the following four symptoms: Small handwriting, feet stuck to the floor, difficulty buttoning buttons and soft voice.…”

Section: Salt Screening Algorithmsmentioning

confidence: 99%

Complete ascertainment of Parkinson disease in the Swedish Twin Registry

Wirdefeldt¹,

Gatz²,

Bakaysa³

et al. 2008

Neurobiology of Aging

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This report describes the ascertainment of Parkinson disease (PD) in all individuals aged 50 years or older (49,814 individuals) from the Swedish Twin Registry. In phase one of the study, all twins were screened for PD using telephone interviews, with a response rate of 72.7%. In phase two, twins with suspected PD were re-contacted to exclude anyone from follow-up who reported parkinsonian symptoms due to diseases other than PD. In the third phase, in-person clinical evaluations were completed for twins who were still considered PD suspects after phase two and for a sample of cotwins. During the clinical evaluations, we also collected blood samples and information about a variety of environmental exposures. Overall prevalence rate for PD was 496 per 100,000 individuals. Among the 132 PD cases identified, there were only three concordant twin pairs. In total 7.2% of PD cases reported a first degree relative with PD.

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Validation of a mail questionnaire for parkinsonism in two languages (German and Italian)

Cited by 30 publications

References 9 publications

Parkinsonism in a population of northern Tanzania: a community-based door-to-door study in combination with a prospective hospital-based evaluation

Parkinsonism in a population of northern Tanzania: a community-based door-to-door study in combination with a prospective hospital-based evaluation

Impaired olfaction and other prodromal features in the Parkinson At‐Risk Syndrome study

Complete ascertainment of Parkinson disease in the Swedish Twin Registry

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