2023
DOI: 10.1097/mat.0000000000002062
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Validation of a Multiscale Computational Model Using a Mock Circulatory Loop to Simulate Cardiogenic Shock

Christian Contarino,
Francesco Chifari,
Gavin A. D’Souza
et al.

Abstract: The objectives of this study are to characterize the hemodynamics of cardiogenic shock (CS) through a computational model validated using a mock circulatory loop (MCL) and to perform sensitivity analysis and uncertainty propagation studies after the American Society of Mechanical Engineers (ASME) Validation and Verification (V&V) guidelines. The uncertainties in cardiac cycle time (T 0), total resistance ( … Show more

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