Validation of bladder health scales and function indices for women’s research

Bavendam, Tamara; Putnam, Sara; Brubaker, Linda; Acevedo-Alvarez, MSME; Marian; Fitzgerald, Colleen M.; Hardacker, Cecilia T.; Hebert‐Beirne, Jeni; Lavender, Missy; Griffith, James W.; Kenton, Kimberly; Simon, Melissa A.; Geynisman‐Tan, Julia; Markland, Alayne D.; Coyne‐Beasley, Tamera; Burgio, Kathryn L.; Lewis, Cora E.; McGwin, Gerald; Vaughan, Camille P.; Williams, Beverly Rosa; Lukacz, Emily S.; Gahagan, Sheila; LaCoursiere, D. Yvette; Nodora, Jesse; Miller, Janis M.; Low, Lisa Kane; Harlow, Bernard L.; Rudser, Kyle; Brady, Sonya S.; Chu, Haitao; Constantine, Melissa L.; Fok, Cynthia S.; Scal, Peter; Rockwood, Todd; Newman, Diane K.; Smith, Ariana L.; Berry, Amanda; Bilger, Andrea; Klusaritz, Heather; Lipman, Terri H.; Stapleton, Ann E.; Wyman, Jean F.; Sutcliffe, Siobhan; James, Aimee S.; Lowder, Jerry L.; Meister, Melanie; Rickey, Leslie; Brault, Marie A; Cunningham, Shayna D.; Barthold, Julia

doi:10.1016/j.ajog.2022.12.319

Cited by 8 publications

(6 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The RISE n‐person assessment is planned as a multicenter observational study of a subset of women in the RISE population‐based cohort study ( n = 525). Eligible participants who have expressed interest in participating in the in‐person assessment are contacted following completion of the initial baseline BHS and BFI 5 to measure BH along with other baseline demographics and medical history. The PLUS Scientific and Data Coordinating Center (SDCC) notifies clinical research sites (CRC) if a RISE participant indicates interest in being screened for the in‐person assessment, which, consistent with BHS/BFI validation parameters, ideally occurs within 8 weeks of BHS/BFI completion (with allowable window up to 12 weeks).…”

Section: Materials and Methodsmentioning

confidence: 99%

“…; (4) is pelvic floor myofascial pain (PFMP), assessed by a clinical evaluator, associated with BH? ; and, (5) is the urogenital microbiome related to BH?…”

Section: Introductionmentioning

confidence: 99%

“…Based on formative studies to inform our study design 5 we elected not to include specific bladder measures (e.g., bladder diaries) or physiological testing, such as noninvasive uroflowmetry and postvoid residual volumes. In our validation study of the Bladder Health Scales and Bladder Function Indices (BHS/BFI), we found poor associations between BH and bladder physiological measures or bladder diary data.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

The RISE FOR HEALTH study: Methods for in‐person assessment and biospecimen collection

Brubaker,

Barthold,

Fitzgerald

et al. 2022

Neurourology and Urodynamics

Self Cite

View full text Add to dashboard Cite

Objectives To describe the methods for the in‐person assessment of the RISE FOR HEALTH (RISE) study, a population‐based multicenter prospective cohort study designed to identify factors that promote bladder health and/or prevent lower urinary tract symptoms in adult women, conducted by the Prevention of Lower Urinary Tract Symptoms Research Consortium (PLUS). Methods and results A subset of RISE participants who express interest in the in‐person assessment will be screened to ensure eligibility (planned n = 525). Eligible consenting participants are asked to complete 15 physical assessments in addition to height and weight, to assess pelvic floor muscle function, musculoskeletal (MSK) status, and pain, and to provide urogenital microbiome samples. Pelvic floor muscle assessments include presence of prolapse, strength, levator attachment integrity (tear) and myofascial pain. MSK tests evaluate core stability, lumbar spine, pelvic girdle and hip pain and function. Participants are asked to complete the Short Physical Performance Battery to measure balance, lower extremity strength, and functional capacity. All participants are asked to provide a voided urine sample and a vaginal swab for microbiome analyses; a subset of 100 are asked to contribute additional samples for feasibility and validation of a home collection of urinary, vaginal, and fecal biospecimens. Results Online and in‐person training sessions were used to certify research staff at each clinical center before the start of RISE in‐person assessments. Standardized protocols and data collection methods are employed uniformly across sites. Conclusions The RISE in‐person assessment is an integral portion of the overall population‐based RISE study and represents an innovative approach to assessing factors hypothesized to promote bladder health and/or prevent lower urinary tract symptoms. Data collected from this assessment will be used to prioritize future research questions and prevention strategies and interventions. This description of the assessment methods is intended to provide methodologic transparency and inform other researchers who join efforts to understand and improve bladder health.

show abstract

Section: Materials and Methodsmentioning

confidence: 99%

“…; (4) is pelvic floor myofascial pain (PFMP), assessed by a clinical evaluator, associated with BH? ; and, (5) is the urogenital microbiome related to BH?…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

The RISE FOR HEALTH study: Methods for in‐person assessment and biospecimen collection

Brubaker,

Barthold,

Fitzgerald

et al. 2022

Neurourology and Urodynamics

Self Cite

View full text Add to dashboard Cite

show abstract

“…1 PLUS investigators have proposed a terminology and research definition for bladder health, 2,3 described a conceptual framework to inform bladder health research, 4 and contributed a validated questionnaire with scales and indices that formally measure bladder health. 5 The PLUS Consortium has completed foundational work to conduct a large, prospective study of bladder health in adult women in the United States. Six articles in this issue describe the methods of the RISE FOR HEALTH (RISE) study.…”

Section: Editorialmentioning

confidence: 99%

“…In 2015, the NIDDK established the transdisciplinary Prevention of Lower Urinary Tract Symptoms (PLUS) Research Consortium to advance bladder health knowledge and to inform intervention studies designed to prevent onset or progression of lower urinary tract symptoms 1 . PLUS investigators have proposed a terminology and research definition for bladder health, 2,3 described a conceptual framework to inform bladder health research, 4 and contributed a validated questionnaire with scales and indices that formally measure bladder health 5 …”

mentioning

confidence: 99%

Editorial

Brubaker

2023

Neurourology and Urodynamics

Self Cite

View full text Add to dashboard Cite

Reliability of Uroflowmetry Pattern Interpretation in Adult Women

Rickey,

Mueller,

Newman

et al. 2024

Neurourology and Urodynamics

View full text Add to dashboard Cite

IntroductionUroflowmetry is often used to assess lower urinary tract symptoms (LUTS). Criteria for characterization of flow patterns are not well established, and subjective interpretation is the most common approach for flow curve classification. We assessed the reliability of uroflowmetry curve interpretation in adult women.Materials and MethodsUroflowmetry studies were obtained in 296 women who participated in an observational cohort study. Four investigators with expertise in female LUTS and urodynamics reviewed and categorized each tracing for interrater reliability. A random subset of 50 tracings was re‐reviewed by each investigator for intrarater reliability. The uroflowmetry tracings were rated using categories of continuous, continuous fluctuating, interrupted, and prolonged. Other parameters included flow rate, voided volume, time to maximum flow, and voiding time. Agreement between raters is summarized with kappa (k) statistics and percentage where at least three raters agreed.ResultsThe mean age of participants was 44.8 ± 18.3 years. Participant age categories were 18–24 years: 20%; 25–34 years: 17%; 35–64 years: 42%; 65+ years: 18%. Nine percent described their race as Asian, 31% Black, 62% White, and 89% were of non‐Hispanic ethnicity. The interrater reliability was highest for the continuous flow category (k = 0.65), 0.47 for prolonged, 0.41 for continuous fluctuating, and 0.39 for interrupted flow curves. Agreement among at least three raters occurred in 74.3% of uroflow curves (69% for continuous, 33% for continuous fluctuating, 23% for interrupted, and 25% for prolonged). For intrarater reliability, the mean k was 0.72 with a range of 0.57–0.85.ConclusionsCurrently accepted uroflowmetry pattern categories have fair to moderate interrater reliability, which is lower for flow curves that do not meet “continuous” criteria. Given the subjective nature of interpreting uroflowmetry data, more consistent and clear parameters may enhance reliability for use in research and as a screening tool for LUTS and voiding dysfunction.Trial RegistrationParent trial: Validation of Bladder Health Instrument for Evaluation in Women (VIEW); ClinicalTrials.gov ID: NCT04016298.

show abstract

Validation of bladder health scales and function indices for women’s research

Cited by 8 publications

References 31 publications

The RISE FOR HEALTH study: Methods for in‐person assessment and biospecimen collection

The RISE FOR HEALTH study: Methods for in‐person assessment and biospecimen collection

Editorial

Reliability of Uroflowmetry Pattern Interpretation in Adult Women

Contact Info

Product

Resources

About