Validation of Electrochemical Sensor for Determination of Manganese in Drinking Water

Abstract

Manganese (Mn) is an essential nutrient for metabolic functions, yet excessive exposure can lead to neurological disease in adults and neurodevelopmental deficits in children. Drinking water represents one of the routes of excessive Mn exposure. Both natural enrichment from rocks and soil, and man-made contamination can pollute groundwater that supplies drinking water for a substantial fraction of the U.S. population. Conventional methods for Mn monitoring in drinking water are costly and involve a long turn-around time. Recent advancements in electrochemical sensing, however, have led to the development of miniature sensors for Mn determination. These sensors rely on a cathodic stripping voltammetry electroanalytical technique on a miniaturized platinum working electrode. In this study, we validate these electrochemical sensors for the determination of Mn concentrations in drinking water against the standard method using inductively coupled plasma mass spectrometry (ICP-MS). Drinking water samples (n = 78) in the 0.03 ppb to 5.3 ppm range were analyzed. Comparisons with ICP-MS yielded 100% agreement, ∼70% accuracy, and ∼91% precision. We envision the use of our system for rapid and inexpensive point-of-use identification of Mn levels in drinking water, which is especially valuable for frequent monitoring where contamination is present.

Highly sensitive electrochemical determination of the SARS-COV-2 antigen based on a gold/graphene imprinted poly-arginine sensor

“…It should be noted that the detection limit is lower with higher linearity than those obtained by the previous MIP-based sensor of ncovNP, and meanwhile, they are also more superior to those presented in some other previous studies. 13,37,38…”

“…It should be noted that the detection limit is lower with higher linearity than those obtained by the previous MIP-based sensor of ncovNP, and meanwhile, they are also more superior to those presented in some other previous studies. 13,37,38 Reproducibility and stability as well as selectivity are great important factors of sensors, thus they were also evaluated. First, eight parallelly constructed MIP/P-Arg/Au/Gr/SPCE were used to test the electrochemical response of 50.0 fM ncovNP for evaluating its reproducibility; relative standard deviation (RSD) value of 3.32% revealed that the MIP/P-Arg/Au/Gr/SPCE has desirable reproducibility (Fig.…”

Assessment of Water Quality and Zooplankton Community Structure in the River Nile, Qena Governorate, Egypt

“…Manganese (Mn) is a metal that is required for metabolic processes (Boselli et al, 2021). The dissolution of minerals from soil by rain, surface, and waste water filtering increases manganese in groundwater sources (Ghosh et al, 2008).…”

Electric Field-Induced Specific Preconcentration to Enhance DNA-Based Electrochemical Sensing of Hg2+ via the Synergy of Enrichment and Self-Cleaning

“…Many methods have been developed to detect Hg, e.g., cold vapor atomic fluorescence, inductively coupled plasma mass spectrometry, fluorescence analysis, and even glucometer readout detection. − Most of them, however, are based on spectroscopy and generally require infrastructure, bulky and expensive instrumentation, and skilled personnel. These are rarely available in underdeveloped areas or at the point of need . In this regard, the ASSURED criterion for a suitable sensing interface method has been formalized by the WHO: Affordable, Sensitive, Specific, User-friendly, Rapid and Robust, Equipment-free, and Deliverable to end-users.…”