Religious and spiritual (R/S) struggles are defined as the occurrence of tension, conflict, or strain that focus on matters of ultimate significance perceived by people as sacred. The widespread prevalence of R/S struggles and the growing demand for research in this area created the need for a brief tool. Recently, the 14-item form of the Religious and Spiritual Struggles Scale was developed and validated (Exline et al. in Psychology of Religion and Spirituality, 2022a). Given the significance of the empirical research on R/S struggles, we implemented the project of structure verification, internal consistency confirmation, reliability, and nomological validation of the Polish variant of the RSS-14 through three separate studies. With respect to the internal structure of the RSS-14, the CFA from three studies confirmed the good fit of the six-factor model, very similar to the one obtained in the original version of the tool. Moreover, both the total score and the subscales had high reliability and acceptable stability over the three studies. With respect to the nomological analyses, R/S struggles were related negatively to life satisfaction, presence of meaning in life, self-esteem, social desirability, religious centrality, and positively with search for meaning, God’s disengagement, poorer health indicators, sleep problems, stress, and cognitive schemas (this category was the new element of our research). Polish 14-item version of the Religious and Spiritual Struggles Scale seems a valuable tool to assess religious strains.