Validation of three-dimensional echocardiography for quantifying the extent of dyssynergy in canine acute myocardial infarction: Comparison with two-dimensional echocardiography

Abstract

Three-dimensional echocardiography is a more accurate means of noninvasively estimating myocardial infarct size in this canine model than two-dimensional echocardiography.

Quantitative Three-Dimensional Wall Motion Analysis Predicts Ischemic Region Size and Location

“…Real-time three-dimensional echocardiography (RT3DE) is well suited for quantification of LV volume, mass, and function 5–7, 10, 14, 15, 20, 25, 28, 32, and for identifying regional wall motion abnormalities during exercise or pharmacological stress that indicate the presence of coronary artery disease 1, 18, 24, 30, 34. RT3DE can be obtained quickly during the critical time period after exercise before the heart rate drops, yet provides complete LV visualization.…”

Quantitative assessment of left ventricular perfusion defects using real-time three-dimensional myocardial contrast echocardiography

“…21 The lack of overestimation of infarct size based on the 3D quantification of dysfunctional mass, in contrast with previous 2D observations, is a consistent feature of those publications. [19][20][21] More recently,Yao et al 22 used an animal model and 3D reconstruction from 2D images to esti- mate myocardial mass after coronary ligation and intravenous injection of contrast. Strong correlations were obtained between the extent of perfusion defects by 3D echocardiography and anatomic measurements of the myocardial mass "at risk," anatomic infarct mass, and salvaged mass after reperfusion.…”

Three-Dimensional Echo: Transition from Theory to Real-Time, A Technology Now Ready for Prime Time

“…67,68 A similar technique was used to quantify the extent of abnormal wall motion in experimental acute myocardial infarction in dogs and was found to be more accurate than 2DE by pathologic determination of infarct size (r ϭ 0.94, SEE ϭ 3.6% versus r ϭ 0.85, SEE ϭ 6.6%). 69 …”