Validity and Reliability of the Turkish Version of Generalized Anxiety Disorder Scale-Revised

Gündüz, Anıl; Gündoğmuş, İbrahi̇m; Engin, Betül; İşler, Aysel; Yasar, Alişan Burak; Gönül, Hatice; Çipil, Arif; Gündüz, Elvan Başak Usta

doi:10.30773/pi.2021.0174

Cited by 3 publications

(2 citation statements)

References 17 publications

(29 reference statements)

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“…GAD is an extremely commonly seen mental health problem that has a negative effect on quality of life. 13 The aim of this study was to analyze the serum S100B, 8-OHdG levels and TOS, TAS, and OSI values of patients newly diagnosed with GAD who had not started treatment, to be able to better understand the underlying neurobiological basis of the etiology of GAD. The study results showed that the S100B and 8-OHdG levels of the patients diagnosed with GAD were higher than those of the control group.…”

Section: Discussionmentioning

confidence: 99%

Biological Markers in Newly Diagnosed Generalized Anxiety Disorder Patients: 8-OHdG, S100B and Oxidative Stress

Oktay,

Asoğlu,

Taskin

et al. 2024

NDT

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Purpose Generalized Anxiety Disorder (GAD) is a chronic disease persisting for at least 6 months, characterized by excessive and continuous anxiety, which leads to evident problems and functional disorders. S100B is a glial protein that plays a role in intercellular communication regulating cell growth and differentiation, and intracellular signal transmission. This study aimed to analyze the serum S100B, 8-OHdG, and oxidative stress levels of patients newly diagnosed with GAD who had not started treatment, to better understand the underlying neurobiological basis of the etiology of GAD. Patients and Methods Forty-four patients diagnosed with GAD according to DSM-5 diagnostic criteria and 44 healthy controls were included in the study. The Beck Anxiety Inventory (BAI) was used to determine the anxiety levels of the GAD patients. The serum S100B, 8-OHdG, total oxidant status (TOS), and total antioxidant status (TAS) levels were measured in the patient and control groups. Results The 8-OHdG values of the GAD group were determined to be statistically significantly higher than those of the control group ( p =0.028). No significant difference was determined between the GAD patients and the control group in respect of the TAS, TOS, and oxidative stress index (OSI) values ( p >0.05). The S100B levels of the GAD group were found to be higher than those of the control group. Conclusion The results of this study showed that there could be DNA damage because of oxidative stress in GAD patients. There is a need for further studies to confirm the role of S100B protein in GAD etiology and pathogenesis.

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Section: Discussionmentioning

confidence: 99%

Biological Markers in Newly Diagnosed Generalized Anxiety Disorder Patients: 8-OHdG, S100B and Oxidative Stress

Oktay,

Asoğlu,

Taskin

et al. 2024

NDT

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“…Another possible explanation is that these psychological factors are less strong predictors or that their impact on FCR may be mediated and moderated by other factors such as worry 35 . Moreover, although the levels of metacognitive beliefs of patients from this study were similar to those observed in cancer patients in other studies (e.g., 11,12,36 ), it should be noted that these scores were lower than those obtained by patients presenting other anxiety disorders (e.g., 37,38 ). Patients' levels of metacognitive beliefs may thus not be characterized as maladaptive.…”

Section: Discussionmentioning

confidence: 99%

Psychological factors associated with clinical fear of cancer recurrence in breast cancer patients in the early survivorship period

et al. 2022

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Objectives Clinical fear of cancer recurrence (FCR) is highly prevalent among breast cancer patients and appears early in the disease trajectory. A better understanding of psychological factors associated with clinical FCR is essential to guide screening and intervention development. This cross‐sectional study aimed to assess the contribution of attentional bias, intrusive thoughts, metacognitive beliefs, intolerance of uncertainty, thought suppression, and worry to clinical FCR in breast cancer patients in the early survivorship period. Methods Seventy‐four patients treated for non‐metastatic breast cancer were enrolled at the end of their treatment. The FCR Inventory‐Short Form (FCRI‐SF) was used to discriminate between the patients with clinical versus nonclinical FCR. Attentional bias to negative and positive cancer‐related and non‐cancer‐related emotional words was assessed with a dot‐probe task. Words were presented for 17, 500, and 1500 ms. Intrusive thoughts and thought suppression were assessed with the White Bear Suppression Inventory, metacognitive beliefs with the Metacognitions Questionnaire‐30, intolerance of uncertainty with the Intolerance of Uncertainty Inventory‐Part A, and worry with the Penn State Worry Questionnaire. Results According to univariate analyses, the patients with clinical FCR (FCRI‐SF ≥13) significantly differed from those with nonclinical FCR in terms of intrusive thoughts (p = 0.002), metacognitive beliefs (p = 0.029), intolerance of uncertainty (p < 0.001), and worry (p < 0.001). Intolerance of uncertainty (odds ratio, OR = 1.06; p = 0.040) and worry (OR = 1.09; p = 0.013) remained in the final logistic regression models. All the patients showed vigilance to cancer‐related words, whether with negative or positive valence, at automatic stages of processing (17 ms). Conclusions Intolerance of uncertainty and worry were the two psychological factors contributing directly to clinical FCR in our cross‐sectional study. In addition, attentional bias did not differentiate breast cancer patients with clinical versus nonclinical FCR. Treatment approaches for clinical FCR in early survivorship care may need to integrate uncertainty and worry management intervention strategies.

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The Validity and Reliability of the Turkish Version of the Meta-Worry Questionnaire

Gündoğmuş¹,

Gündüz²,

Engin³

et al. 2022

Archives of Neuropsychiatry

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Validity and Reliability of the Turkish Version of Generalized Anxiety Disorder Scale-Revised

Cited by 3 publications

References 17 publications

Biological Markers in Newly Diagnosed Generalized Anxiety Disorder Patients: 8-OHdG, S100B and Oxidative Stress

Biological Markers in Newly Diagnosed Generalized Anxiety Disorder Patients: 8-OHdG, S100B and Oxidative Stress

Psychological factors associated with clinical fear of cancer recurrence in breast cancer patients in the early survivorship period

The Validity and Reliability of the Turkish Version of the Meta-Worry Questionnaire

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