Validity and reliability of the NEI VFQ-25 questionnaire in Indonesian leprosy patients

Rahayu, Tri; Menaldi, Sri Linuwih; Irawati, Yunia; Andayani, Gitalisa; Presialia, Athira; Harini, Melinda; Friska, Dewi

doi:10.1016/j.cegh.2022.101039

Cited by 5 publications

(4 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The subscale responses were graded on a scale of 0 to 100 based on published literature, where higher scores represent better VRQoL. The subscale items were averaged to form subscales, and the sum of averages resulted in a composite score ( 14 , 15 ).…”

Section: Methodsmentioning

confidence: 99%

Vision-related quality of life among patients with keratoconus: a cross sectional study

Al Zabadi,

Shehadeh,

Amro

et al. 2023

Front. Med.

View full text Add to dashboard Cite

PurposeThe present study aimed to evaluate the quality of life of keratoconus patients residing in Nablus city, Palestine. Furthermore, we investigated the possible correlation between Pentacam topographic indices and the quality of life of patients with keratoconus.MethodsThis cross-sectional study evaluated keratoconus patients at An-Najah University Hospital in 2019, diagnosed through clinical examination and corneal tomography. A control group was randomly selected from non-keratoconus patients with normal tomography. The NEI-VFQ-25 questionnaire was administered during face-to-face interviews to compare both groups. NEI-VFQ-25 assesses vision-related quality of life and is a validated tool.ResultsKeratoconus patients’ quality of life is significantly impacted, mainly in near and distant vision, general vision, mental health, and social health, but not in general health, ocular pain, color vision, role difficulties, or dependency. Visual acuity is significantly affected in both eyes of keratoconus patients.ConclusionPatients with keratoconus exhibit a decreased quality of life related to vision, with physical, emotional, and social impairments demonstrated by the NEI-VFQ-25 when compared to controls. Since keratoconus patients are typically young adults in their productive years, understanding their concerns about their future is an important public health aspect that can aid in modifying their treatments. By addressing the specific needs of this patient population, healthcare providers can better support their long-term well-being and quality of life.

show abstract

Section: Methodsmentioning

confidence: 99%

Vision-related quality of life among patients with keratoconus: a cross sectional study

Al Zabadi,

Shehadeh,

Amro

et al. 2023

Front. Med.

View full text Add to dashboard Cite

show abstract

“…It was administered by the interviewer as a printout at the study site. Subjects who were illiterate were assisted in filling out the questionnaire [ 13 ]. To prevent from being bias when assisting patients completing the questionnaire, the interviewers had been trained on how to ask the questions without directing the participants’ answers and to use language understood by the subjects.…”

Section: Methodsmentioning

confidence: 99%

Vision-related quality of life among released from treatment cases of leprosy evaluated with NEI-VFQ-25: a cross-sectional study

Irawati,

Andayani,

Rahayu

et al. 2023

BMC Ophthalmol

Self Cite

View full text Add to dashboard Cite

Background People with leprosy who have been declared Release From Treatment (RFT) are often not aware of the leprosy sequelae possibility which can decrease their quality of life. This could be because they have been adapting for a long time hence they do not feel the need to see physicians. This study seeks to compare the results of Vision-Related Quality of Life (VR-QoL) among RFT persons based on the National Eye Institute Visual Functioning Questionnaire–25 (NEI-VFQ-25) and WHO grading disability based on physical examination. Methods A cross-sectional study of 325 RFT subjects from leprosy communities (Singkawang, West Kalimantan and Tangerang, Banten) was conducted between 2018 and 2019. We used the NEI-VFQ-25 questionnaire that had been validated and translated into Indonesian and distributed to the leprosy population. Relationships and comparisons among variables were evaluated using Kruskal–Wallis and Mann–Whitney tests. Results There were three main results: The median composite score of VR-QoL for WHO grade 0, 1, and 2 disabilities has decreased by 13%, 25.5%, and 30% of the maximum value, respectively. Of the total, eleven subscales were statistically significant between WHO grading disability and VR-QoL based on the NEI-VFQ-25 (p < 0.05). The comparison between grade 0 and grade 2 disability in all subscales was statistically significant (p < 0.05). Conclusions The grade of disability is related to their VR-QoL assessment using the NEI-VFQ-25 questionnaire. Thus, it can be used as an initial screening in primary healthcare settings to increase awareness of disability before a thorough physical examination.

show abstract

“…Published clinical trials have reported results such as visual acuity improvement and maintenance and improved National Eye Institute Visual Function Questionnaire-25 scores (NEI VFQ-25, which measures vision-related functioning and the influence of vision problems on health-related quality of life). Other results included an improved fundus perimetry deviation index and electroretinography (ERG) parameters, temporary improvement in visual acuity and increase in retinal sensitivity of pupillary response, and tolerable safety profiles, among other outcomes, although results varied among disease genotypes [177][178][179][180]. On the other hand, in contrast to FSCs, applications of adult MSCs that have been investigated in preclinical and clinical studies, such as the use of intravitreal injection of BM-MSCs in patients with advanced RP, have thus far demonstrated results that have not been convincing [181].…”

Section: Published Evidence Of Regenerative-based Therapies In Ophtha...mentioning

confidence: 99%

Beyond Vision: An Overview of Regenerative Medicine and Its Current Applications in Ophthalmological Care

Santa Cruz-Pavlovich,

Bolaños-Chang,

Del Rio-Murillo

et al. 2024

Cells

View full text Add to dashboard Cite

Regenerative medicine (RM) has emerged as a promising and revolutionary solution to address a range of unmet needs in healthcare, including ophthalmology. Moreover, RM takes advantage of the body’s innate ability to repair and replace pathologically affected tissues. On the other hand, despite its immense promise, RM faces challenges such as ethical concerns, host-related immune responses, and the need for additional scientific validation, among others. The primary aim of this review is to present a high-level overview of current strategies in the domain of RM (cell therapy, exosomes, scaffolds, in vivo reprogramming, organoids, and interspecies chimerism), centering around the field of ophthalmology. A search conducted on clinicaltrials.gov unveiled a total of at least 209 interventional trials related to RM within the ophthalmological field. Among these trials, there were numerous early-phase studies, including phase I, I/II, II, II/III, and III trials. Many of these studies demonstrate potential in addressing previously challenging and degenerative eye conditions, spanning from posterior segment pathologies like Age-related Macular Degeneration and Retinitis Pigmentosa to anterior structure diseases such as Dry Eye Disease and Limbal Stem Cell Deficiency. Notably, these therapeutic approaches offer tailored solutions specific to the underlying causes of each pathology, thus allowing for the hopeful possibility of bringing forth a treatment for ocular diseases that previously seemed incurable and significantly enhancing patients’ quality of life. As advancements in research and technology continue to unfold, future objectives should focus on ensuring the safety and prolonged viability of transplanted cells, devising efficient delivery techniques, etc.

show abstract

Validity and reliability of the NEI VFQ-25 questionnaire in Indonesian leprosy patients

Cited by 5 publications

References 17 publications

Vision-related quality of life among patients with keratoconus: a cross sectional study

Vision-related quality of life among patients with keratoconus: a cross sectional study

Vision-related quality of life among released from treatment cases of leprosy evaluated with NEI-VFQ-25: a cross-sectional study

Beyond Vision: An Overview of Regenerative Medicine and Its Current Applications in Ophthalmological Care

Contact Info

Product

Resources

About