Value of Measuring Myocardial Performance Index by Tissue Doppler Echocardiography in Normal and Diseased Heart

Abstract

SUMMARYMyocardial performance index (MPI) is a simple and reproducible method for the assessment of overall cardiac function. In this study, we evaluated the applicability and usefulness of pulsed-wave tissue Doppler echocardiography (TDE) as a tool to calculate MPI in comparision with a conventional Doppler method.Twenty-five patients with previous myocardial infarction (MI) and 15 healthy subjects were included. In order to calculate MPI by TDE, isovolumetric contraction time (IVCT), isovolumetric relaxation time (IVRT), and ejection time (ET) were measured at four different sites in the mitral annulus: septum, lateral, anterior, and inferior. MPI was calculated by dividing the sum of IVCT and IVRT by ET at each site of measurement. The mean MPI value was found by dividing the sum of these MPI values into four. The same parameters were measured using the mitral inflow and left ventricular outflow velocity time intervals by a conventional method.MPI by TDE correlated well with conventional MPI in healthy subjects (r = 0.81, P < 0.0001). Although it continued to be statistically significant, the correlation between the two methods of measuring MPI, TDE and conventional, in patients with previous MI was not as high as it was in healthy individuals (P < 0.001, r = 0.62). This is due to the lesser degree of correlation between IVRT and IVCT values obtained by TDE and the conventional method (r = 0.49, P < 0.05; r = 0.56, P < 0.05; respectively).In conclusion, this study has demonstrated that MPI could be measured by tissue Doppler and that it correlated well with conventional MPI. Moreover, MPI by TDE has the advantage of assessing both regional and global myocardial performance. (Jpn Heart J 2003; 44: 403-416)

Effect of cilnidipine on left ventricular function in hypertensive patients as assessed by tissue Doppler Tei index

“…It is reported that the normal value of TDI Tei index range from 0.29-0.36. 11,16,18 The present study illustrates that TDI Tei index is higher in hypertensives, and more prominent in LVH group, but E/A shows no difference between NLVH and LVH groups, which suggests that TDI Tei index is a sensitive parameter for evaluation of global ventricular function before developing ventricular hypertrophy. The present study also supports the opinion that systolic dysfunction coexists with diastolic dysfunction in hypertensives.…”

“…Tei index was reported to be simple, reproducible and independent of HR and blood pressure. 25 Tissue Doppler imaging Tei index was used to evaluate LV function in patients with dilate cardiomyopathy, 16 myocardial infarction 18 and hypertension. 11 In those disease states, Tei index was found to be higher than in normal subjects, and TDI Tei index correlated well with traditional Tei index.…”

“…17 Studies that use Tei index derived from TDI demonstrated that TDI Tei index correlated with conventional Tei index very well. 16,18 Cilnidipine is a long-acting calcium channel blocker, which blocks not only L-type Ca 2 þ channel in blood vessel but also the N-type Ca 2 þ channel in sympathetic nerve endings. 19,20 Clinical studies demonstrate that cilnidipine is an effective antihypertensive drug.…”

Prognostic Value of Cardiac Time Intervals by Tissue Doppler Imaging M-Mode in Patients With Acute ST-Segment–Elevation Myocardial Infarction Treated With Primary Percutaneous Coronary Intervention

“…4,5 Tissue Doppler imaging (TDI) is an alternative noninvasive approach to obtain the cardiac time intervals and thereby the MPI. 6,7 With this method, the time intervals can be obtained from 1 projection and 1 cardiac cycle. In contrast, with the conventional method described by Tei et al, 5 the time intervals are obtained from 2 projections and at least 2 cardiac cycles 4,5 and may therefore be prone to errors caused by heart rate variability, which is not a concern with TDI.…”

Beta talasemi majorlu çocuk ve ergenlerde doku Doppler yöntemiyle diyastolik işlevlerin değerlendirilmesi

“…Therefore, regional wall motion disorders develop in the early phase of the disease, although general cardiac function is normal (4). Newly developed tissue Doppler imaging intended to demonstrate cardiac dysfunction in the early phase has started to be used in various patients groups and has been shown to be superior to conventional echocardiographic methods (5)(6)(7)(8)(9).…”