Value of N-Terminal Pro-Brain Natriuretic Peptide in Predicting Perioperative Complications Following Spine Surgery

Acarbaş, Arsal

doi:10.1016/j.wneu.2019.10.012

Cited by 4 publications

(4 citation statements)

References 20 publications

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“…Increased preoperative B-type NPs appear also to have prognostic value for mortality and poor cardiovascular outcomes. However, perioperative changes and postoperative B-type NPs for prognosis and for risk prediction are less well studied 8,9,12–14,59–108 . Current European guidelines 109,110 provide guidance on the use of cardiac biomarkers that differ in terms of strength of the recommendation and on the population to be submitted for cardiac biomarker evaluation.…”

Section: Introductionmentioning

confidence: 99%

ESAIC focused guideline for the use of cardiac biomarkers in perioperative risk evaluation

Lurati Buse,

Bollen Pinto,

Abelha

et al. 2023

European Journal of Anaesthesiology

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BACKGROUND In recent years, there has been increasing focus on the use of cardiac biomarkers in patients undergoing noncardiac surgery. AIMS The aim of this focused guideline was to provide updated guidance regarding the pre-, post- and combined pre-and postoperative use of cardiac troponin and B-type natriuretic peptides in adult patients undergoing noncardiac surgery. METHODS The guidelines were prepared using Grading of Recommendations Assessment Development and Evaluation (GRADE) methodology. This included the definition of critical outcomes, a systematic literature search, appraisal of certainty of evidence, evaluation of biomarker measurement in terms of the balance of desirable and undesirable effects including clinical outcomes, resource use, health inequality, stakeholder acceptance, and implementation. The panel differentiated between three different scopes of applications: cardiac biomarkers as prognostic factors, as tools for risk prediction, and for biomarker-enhanced management strategies. RESULTS In a modified Delphi process, the task force defined 12 critical outcomes. The systematic literature search resulted in over 25,000 hits, of which 115 full-text articles formed the body of evidence for recommendations. The evidence appraisal indicated heterogeneity in the certainty of evidence across critical outcomes. Further, there was relevant gradient in the certainty of evidence across the three scopes of application. Recommendations were issued and if this was not possible due to limited evidence, clinical practice statements were produced. CONCLUSION The ESAIC focused guidelines provide guidance on the perioperative use of cardiac troponin and B-type natriuretic peptides in patients undergoing noncardiac surgery, for three different scopes of application.

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Section: Introductionmentioning

confidence: 99%

ESAIC focused guideline for the use of cardiac biomarkers in perioperative risk evaluation

Lurati Buse,

Bollen Pinto,

Abelha

et al. 2023

European Journal of Anaesthesiology

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“…BNP and NT-proBNP are well-known predictive factors for major cardiac events, however, recent researches have demonstrated the clinical and prognostic implications of BNP and NT-proBNP in predicting AKI in several medical settings, such as critical illness ( 18 ), severe burn ( 16 ), coronary heart disease ( 14 ) and cardiac surgery ( 19 , 20 ), but, its relationship with AKI after noncardiac surgery had rarely been investigated. Till now, to our knowledge, only four studies have addressed this issue ( 21 , 25 – 27 ). The study by Cardinale et al included 2,179 patients solely undergoing lung cancer surgery, a 10% incidence of AKI was reported, and, among the independent predictors of AKI, serum Scr [area under the curve (AUC) 0.70 (95% CI 0.67–0.74)] and NT-proBNP [AUC 0.71 (95% CI 0.67–0.74)] provided the highest predictive accuracy, and their combination further significantly improved AKI prediction [AUC 0.74 (95% CI 0.71–0.77)] ( 25 ).…”

Section: Discussionmentioning

confidence: 99%

“…Serum BNP level was useful for predicting the early development of AKI after LDLT (AUC 0.69) ( 21 ). Acarbas in his study mentioned the NT-proBNP level in patients undergoing sine surgery could be a valuable prognostic marker for several post-operative complications including acute renal failure ( 27 ). The study by Zhao included 7,248 patients undergoing non-cardiac surgery and the incidence of AKI was 6.1%.…”

Section: Discussionmentioning

confidence: 99%

“…Further studies demonstrated the predictive value of serum NT-proBNP in PO-AKI after cardiac surgery both in adults and children ( 19 , 20 , 24 ). But, the investigations on the predictive value of serum NT-proBNP in PO-AKI after non-cardiac surgery are rare ( 21 , 25 – 27 ). Patients undergoing cardiac surgery usually experience significant haemodynamic instability and severe PO-AKI is common ( 19 , 26 ).…”

Section: Introductionmentioning

confidence: 99%

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The Predictive Value of Pre-operative N-Terminal Pro-B-Type Natriuretic Peptide in the Risk of Acute Kidney Injury After Non-cardiac Surgery

Liu

Pang²,

Tang³

et al. 2022

Front. Med.

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ObjectiveTo evaluate the association between N-terminal pro-B-type natriuretic peptide (NT-proBNP) and risk of post-operative acute kidney injury (PO-AKI).MethodsThe electronic medical records and laboratory results were obtained from 3,949 adult patients (≥18 years) undergoing non-cardiac surgery performed between 1 October 2012 to 1 October 2019 at the Third Xiangya Hospital, Central South University, China. Collected data were analyzed retrospectively.ResultsIn all, 5.3% (209 of 3,949) of patients developed PO-AKI. Pre-operative NT-proBNP was an independent predictor of PO-AKI. After adjustment for significant variables, OR for AKI of highest and lowest NT-proBNP quintiles was 1.96 (95% CI, 1.04–3.68, P = 0.008), OR per 1-unit increment in natural log transformed NT-proBNP was 1.20 (95% CI, 1.09–1.32, P < 0.001). Compared with clinical variables alone, the addition of NT-proBNP modestly improved the discrimination [change in area under the curve(AUC) from 0.82 to 0.83, ΔAUC=0.01, P = 0.024] and the reclassification (continuous net reclassification improvement 0.15, 95% CI, 0.01–0.29, P = 0.034, improved integrated discrimination 0.01, 95% CI, 0.002–0.02, P = 0.017) of AKI and non-AKI cases.ConclusionsResults from our retrospective cohort study showed that the addition of pre-operative NT-proBNP concentrations could better predict post-operative AKI in a cohort of non-cardiac surgery patients and achieve higher net benefit in decision curve analysis.

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Letter to the Editor Regarding “Perioperative Complications Associated with Severity of Anemia in Geriatric Patients Undergoing Spinal Procedures”

Gökçek

Biteker

2020

World Neurosurgery

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Value of N-Terminal Pro-Brain Natriuretic Peptide in Predicting Perioperative Complications Following Spine Surgery

Cited by 4 publications

References 20 publications

ESAIC focused guideline for the use of cardiac biomarkers in perioperative risk evaluation

ESAIC focused guideline for the use of cardiac biomarkers in perioperative risk evaluation

The Predictive Value of Pre-operative N-Terminal Pro-B-Type Natriuretic Peptide in the Risk of Acute Kidney Injury After Non-cardiac Surgery

Letter to the Editor Regarding “Perioperative Complications Associated with Severity of Anemia in Geriatric Patients Undergoing Spinal Procedures”

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