Value of transrectal power Doppler sonography in the detection of low-risk prostate cancers

Sauvain, J.L.; Sauvain, E.; Rohmer, P; Louis, D.; Nader, Nader D.; Papavero, R.; Bremon, J.M.; Jehl, J.

doi:10.1016/j.diii.2012.09.003

Cited by 17 publications

(25 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Various authors reported additional value of the Doppler techniques over TRUS [9,16,18]. For Eisenberg et al [22], adding PDS to TRUS improved specificity from 47 to 74 %, although the sensitivity decreased from 58 to 47 %.…”

Section: Discussionmentioning

confidence: 99%

“…The power Doppler mode searched for the presence of intralesional vessels in a suspect lesion in the B-mode sonography. A visible lesion in B mode was hypervascularised if at least one vessel in this lesion was clearly identified [18] (Fig. 1).…”

Section: Ultrasound Semiology and Power Dopplermentioning

confidence: 99%

“…In the same session, the radiologist (because of PDS) guided the biopsies performed by the urologist surgeon. Twelve samples were taken systematically according to the recommendations for good biopsy practices [18]. One to three additional samples were added in the case of suspect lesions in the PDS.…”

Section: Biopsiesmentioning

confidence: 99%

“…Combining different ultrasound modalities and the new ultrasound techniques can potentially improve PCa detection, grading, and staging. [14][15][16][17][18]. This paper aims to assess a prospective series of 429 patients for the probability of having a low-risk lesion that could require active surveillance (AS) after prostate biopsies in patients with a normal digital rectal examination (DRE), a PSA level between 4 and 10 ng/ml, and a normal or abnormal TRUS-PDS examination.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Limiting overdiagnosis of low-risk prostate cancer through an evaluation of the predictive value of transrectal and power Doppler ultrasonography

Sauvain

Papavero

et al. 2016

J Ultrasound

View full text Add to dashboard Cite

Purpose Overdiagnosis induced by prostate cancer screening makes necessary a better selection of candidate patients for prostate biopsy. The objective of our study is to assess the probability of having a high-or low-risk lesion that could require active surveillance (AS) after biopsies and a normal or abnormal examination, including transrectal and power Doppler ultrasonography (TRUS-PDS). Methods Four hundred and twenty-nine consecutive patients with a PSA level \10 ng/ml and a normal digital rectal examination (DRE) had guided biopsies in a prospective study. We used D'Amico's criteria to assess the risk of a biological recurrence and Dall'Era's criteria to assess possible AS. The TRUS-PDS was considered positive if one biopsy was positive in the same sextant as the suspect image. Results One hundred and seventy-seven out of 429 (41 %) T1c cancers were diagnosed; 131 out of 177 (74 %) could be qualified as low risk, and 119 out of 177 (67 %) could require AS. The TRUS-PDS was normal in 285 of 429 patients (66 %). With a normal TRUS-PDS, the probability of not having cancer with a high or intermediate risk was 96 % (negative predictive value). With an abnormal TRUS-PDS, the probability of having a positive biopsy was 59 %, and the probability of having a significant cancer was 30 %, according to the Dall'Era criteria. When TRUS-PDS was normal, these probabilities significantly decreased to 32 and 5 %, respectively (p \ 0.01). Conclusions Patients with a PSA level \10 ng/ml, a normal DRE, and a normal TRUS-PDS have a less than 5 % risk of high-or intermediate-risk cancer.Keywords Prostate cancer Á Transrectal ultrasound Á Power Doppler sonography Á Overdiagnosis Á Low risk cancer Á High-risk cancer Sommario Scopo Lo screening per la prevenzione del cancro alla prostata può portare a un eccessivo di falsi positivi; pertanto è necessaria un'attenta selezione dei pazienti candidati alla biopsia della prostata. L'obiettivo del nostro studio è quello di valutare la probabilità di avere una lesione ad alto o basso rischio che potrebbe richiedere una sorveglianza attiva (AS) dopo biopsia, e un normale o anormale esame rettale trans and power Doppler (TRUS-PDS). Metodi In uno studio prospettico, sono state eseguite 429 biopsie in pazienti consecutivi con un livello di PSA \10 ng/ml e un DRE normale. Sono stati usati i criteri di D'Amico per valutare il rischio di una recidiva biologica, e quelli di Dall'Era per la sorveglianza attiva (AS). Se anche una sola biopsia risultava positiva, anche la TRUS-PDS di conseguenza era considerata positivo. Risultati Sono stati diagnosticati 177 tumori/429 (41 %) tumori T1c: 131/177 (74 %) Sono stati qualifications come a basso rischio e 119/177 (67 %) possono richiedere un AS.La TRUS -PDS era normale in 285 dei 429 pazienti (66 %). Con un normale esame di TRUS -PDS, la probabilità di non avere un cancro con un rischio elevato o intermedio era del 96 % (valore predittivo negativo). Con una TRUS-PDS positivo per (2016( ) 19:275-280 DOI 10.1007 neoplasia, la probabilità di av...

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Ultrasound Semiology and Power Dopplermentioning

confidence: 99%

Section: Biopsiesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Limiting overdiagnosis of low-risk prostate cancer through an evaluation of the predictive value of transrectal and power Doppler ultrasonography

Sauvain

Papavero

et al. 2016

J Ultrasound

View full text Add to dashboard Cite

show abstract

“…Studies suggest that on CDUS and PDUS, hypervascular and hypovascular lesions are associated with higher and lower Gleason scores, respectively (Fig. 1B) (17,18).…”

Section: Color and Power Doppler Ultrasoundmentioning

confidence: 99%

Utility of Ultrasound in the Diagnosis, Treatment, and Follow-up of Prostate Cancer: State of the Art

2016

View full text Add to dashboard Cite

Prostate cancer screening currently consists of serum prostatespecific antigen and digital rectal examination, followed by transrectal ultrasound-guided biopsy for diagnostic confirmation. Although the current paradigm of prostate cancer screening has led to a decrease in advanced disease and cancer-related mortality, these techniques have limitations in terms of sensitivity and specificity, resulting in missed cancers that are clinically significant and the overdetection of clinically insignificant cancers. New imaging techniques and technologies are required to improve the detection of prostate cancer. This article summarizes the use of novel ultrasound techniques and technologies in the detection, biopsy, and treatment of prostate cancer.

show abstract

TRUS Biopsy: Is There Still a Role?

Leapman

Shinohara

2016

The Prostate Cancer Dilemma

View full text Add to dashboard Cite

Value of transrectal power Doppler sonography in the detection of low-risk prostate cancers

Abstract: A normal PDS in patients presenting a PSA level less than 10 ng/ml and a DRE without anomaly may be used to put off the indication for a biopsy in order to reduce their number as well as the risks of overtreatment for a latent cancer.

Cited by 17 publications

References 32 publications

Limiting overdiagnosis of low-risk prostate cancer through an evaluation of the predictive value of transrectal and power Doppler ultrasonography

Limiting overdiagnosis of low-risk prostate cancer through an evaluation of the predictive value of transrectal and power Doppler ultrasonography

Utility of Ultrasound in the Diagnosis, Treatment, and Follow-up of Prostate Cancer: State of the Art

TRUS Biopsy: Is There Still a Role?

Contact Info

Product

Resources

About