Values for Macular Perimetry Using the MP-1 Microperimeter in Normal Subjects

Abstract

Purpose: To establish values for the fixation pattern and macular sensitivity to light in healthy subjects using the MP-1 microperimeter (Nideck Technologies, Vigonza, Italy). Method: A prospective study of 37 healthy subjects (age: 19–71 years), approved by the institutional review board. Full-threshold microperimetry of the central 12° of the retina (the macula) was performed prospectively, utilizing 16 points with the MP-1. The fixation stability was simultaneously recorded during microperimetry testing. The relationship between the fixation pattern and light sensitivity with age was calculated using linear regression analysis. Results: Microperimetry was performed on 66 eyes. Total mean sensitivity was 18.33 dB (range: 13.0–19 dB). Mean macular sensitivities at 2°, 4° and 6° as measured by the MP-1 were 18.4 ± 2.0, 18.2 ± 2.3 and 18.2 ± 2.1 dB, respectively. The linear regression analysis revealed a 0.019240, 0.0248 and 0.0285 dB per year age-related decline in mean macular sensitivity at 2°, 4° and 6° from the center of the macula, respectively. The total mean fixation stability values within 2° and 4° were 86 and 96%, respectively. The linear regression analysis also revealed a 0.344% and 0.122% per year decline in age-related fixation stability within 2° and 4°, respectively. There were no statistically significant differences between the median retinal sensitivity or fixation stability values for sex or race in the study. Conclusions: The MP-1 may be a reliable tool to measure macular sensitivity. Among normal healthy subjects, there was a linear decline in light sensitivity with increasing age.

Long-term follow-up with optical coherence tomography and microperimetry in eyes with metamorphopsia after macula-off retinal detachment repair

“…20 In healthy subjects aged 19-71 years, MS ranges from 13 to 19 (mean 18.3) dB with a linear decline in sensitivity with increasing age. 21 In our patients, mean MS threshold slowly improved approaching normal levels at 3 or 6 months post-operatively except in patient 3. Interestingly the weak correlation between our post-operative MP-1 and BCVA results indicate that mean MS is a functional parameter relatively independent from BCVA after macula-off RD repair.…”

Regional Macular Light Sensitivity Changes in Myopic Chinese Adults: An MP1 Study

“…24 In the present study, we suggest that the fixation stability within 2°and 4°in myopic subjects with normal corrected visual acuity did not need to be taken into consideration when analyzing the results.…”

“…[15][16][17][18][19][20] The parameters in normal subjects of different age, sex, and race, as well as interand intraexaminer reliability have been studied to determine the effects of these extraneous variables on measurements. 22,24 In these reports, MP1 measurements exhibited high inter-and intraexaminer reliability. Macular function measured by MP1 in normal subjects decreased with age, but had no apparent relationship with sex and race, 22,24 providing support for further usage of MP1 in clinical applications.…”

“…22,24 In these reports, MP1 measurements exhibited high inter-and intraexaminer reliability. Macular function measured by MP1 in normal subjects decreased with age, but had no apparent relationship with sex and race, 22,24 providing support for further usage of MP1 in clinical applications. In high myopia eyes, many studies have reported declines in parameters of visual function such as corrected visual acuity, 25 visual field, 26 color vision, 27 light sense, 27 and contrast sensitivity.…”

Retinal sensitivity assessed by microperimetry and corresponding retinal structure and thickness in resolved central serous chorioretinopathy

“…The RS assessed by MP was known to be the same within the central 61 of the macula in normal subjects. 31 Therefore, the correlation analysis between RS and RPT needs to be stratified according to the test location. The correlation coefficient between RS and RPT decreased after controlling for EPIS status and test location.…”