“… 1 Leaflet plication is an important valvuloplasty technique, particularly when resuspending a dilated valve in a downsized tube graft or native aortic root. 2 , 3 , 4 , 5 We have observed that central plication of multiple leaflets often leads to suboptimal repair with clinically significant central regurgitation, a possible consequence of approaches not accounting for native leaflet proportions and leaflet–leaflet interactions. Herein, we describe a repair strategy subsequently validated ex vivo that addresses these concerns to prevent residual central regurgitation following AVr.…”