Vancomycin-induced linear Immunoglobulin A bullous dermatosis

Phyu, Htay; Kobayashi, Takaaki; Rastogi, Prerna; Cho, Christine

doi:10.1136/bcr-2019-233281

Cited by 4 publications

(3 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…55 Drug-induced LAD (DILAD) has been described in adults and, less frequently, in children. In approximately one third of patients, the onset of LAD appears to be induced by exposure to other drugs than vancomycin 56,57 (Table 3).…”

Section: Drug As Soci Ationmentioning

confidence: 99%

S2k guidelines on diagnosis and treatment of linear IgA dermatosis initiated by the European Academy of Dermatology and Venereology

Caux,

Patsatsi,

Karakioulaki

et al. 2024

Acad Dermatol Venereol

View full text Add to dashboard Cite

IntroductionLinear IgA dermatosis (LAD) is a rare subepidermal autoimmune bullous disease (AIBD) defined by predominant or exclusive immune deposits of immunoglobulin A at the basement membrane zone of skin or mucous membranes. This disorder is a rare, clinically and immunologically heterogeneous disease occurring both in children and in adults. The aim of this project is to present the main clinical features of LAD, to propose a diagnostic algorithm and provide management guidelines based primarily on experts' opinion because of the lack of large methodologically sound clinical studies.MethodsThese guidelines were initiated by the European Academy of Dermatology and Venereology (EADV) Task Force Autoimmune Bullous Diseases (AIBD). To achieve a broad consensus for these S2k consensus‐based guidelines, a total of 29 experts from different countries, both European and non‐European, including dermatologists, paediatric dermatologists and paediatricians were invited. All members of the guidelines committee agreed to develop consensus‐based (S2k) guidelines. Prior to a first virtual consensus meeting, each of the invited authors elaborated a section of the present guidelines focusing on a selected topic, based on the relevant literature. All drafts were circulated among members of the writing group, and recommendations were discussed and voted during two hybrid consensus meetings.ResultsThe guidelines summarizes evidence‐based and expert opinion‐based recommendations (S2 level) on the diagnosis and treatment of LAD.ConclusionThese guidelines will support dermatologists to improve their knowledge on the diagnosis and management of LAD.

show abstract

Section: Drug As Soci Ationmentioning

confidence: 99%

S2k guidelines on diagnosis and treatment of linear IgA dermatosis initiated by the European Academy of Dermatology and Venereology

Caux,

Patsatsi,

Karakioulaki

et al. 2024

Acad Dermatol Venereol

View full text Add to dashboard Cite

show abstract

“…Milia and scar development are not expected. Subepidermal blisters are characterized by linear IgA deposits in the BMZ on direct immunofluorescence (DIF) [47,53,54].…”

Section: Epidermolysis Bullosa Acquisita (Eba)mentioning

confidence: 99%

“…MMP-like EBA mainly affects mucous membranes such as mouth, pharynx, esophagus, conjunctiva, anus, genital area, and respiratory tract and heals with scarring. As in MMP, organ-specific complications may occur due to scar formation in the mucous membranes [54,55].…”

Section: Epidermolysis Bullosa Acquisita (Eba)mentioning

confidence: 99%

Skin Blister Formation and Subepidermal Bullous Disorders

Aygar¹,

Gönül²

2023

Wound Healing - Recent Advances and Future Opportunities

View full text Add to dashboard Cite

Blistering diseases comprise a large group of clinically polymorphic and sometimes devastating diseases. Blistering diseases are evaluated according to the level of the blister, the mechanism of blister formation and the type of inflammation. There are many connections in the normal structure of the skin that hold the cells together. These connections both hold the cells in the epidermis together and ensure that these cells attach to the basement membrane. As a result of damage to these connections by genetic, immune, infectious or physical reasons, intercellular connections are broken and blistering developments due to the accumulation of extracellular fluid in the intercellular spaces. Autoimmune bullous diseases are classified according to the decomposition site of the epidermis. While the pemphigus group is used to classify diseases with intraepidermal separation, the pemphigoid group diseases are used to classify diseases with subepidermal separation. In this section, pemphigoid group diseases, such as bullous pemphigoid, mucous membrane pemphigoid, acquired epidermolysis bullosa, linear IgA bullous dermatosis, and anti-p200 pemphigoid, will be explained with a brief introduction to blistering diseases of the skin.

show abstract

Vancomycin

2020

Reactions Weekly

View full text Add to dashboard Cite

Vancomycin-induced linear Immunoglobulin A bullous dermatosis

Cited by 4 publications

References 5 publications

S2k guidelines on diagnosis and treatment of linear IgA dermatosis initiated by the European Academy of Dermatology and Venereology

S2k guidelines on diagnosis and treatment of linear IgA dermatosis initiated by the European Academy of Dermatology and Venereology

Skin Blister Formation and Subepidermal Bullous Disorders

Vancomycin

Contact Info

Product

Resources

About