Variables associated with asthma control among adult patients

Al‐Qerem, Walid; Jarab, Anan S.; Heshmeh, Shrouq Abu; Ling, Jonathan

doi:10.1080/02770903.2022.2144351

Cited by 3 publications

(1 citation statement)

References 51 publications

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“…6 The control of asthma has been reported to be low in many countries. 1,2,7,8 In a large-scale investigation of adult asthma control in the Middle East and North Africa, less than 30% of asthmatics were controlled with about 42% being uncontrolled. 7 Similar results were reported in a previous study conducted in Northern Jordan, 9 while in Southern Jordan, asthma control among adults was documented to be 45.2%.…”

Section: Introductionmentioning

confidence: 99%

Role of Community Pharmacist in Asthma Management: Knowledge, Attitudes and Practice

Jarab,

Al-Qerem,

Alzoubi

et al. 2024

JMDH

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Purpose To investigate knowledge, attitude, and practice of asthma management counseling and the perceived barriers by community pharmacists. Methods This cross-sectional study was conducted on 416 community pharmacists using an online-based questionnaire. The questionnaire included five parts that assessed socio-demographics and medical references used to seek drug-related information, pharmacists’ knowledge (7 items), attitudes (5 items), practice (22 items) and the barriers for the provision of asthma management counseling (10 items). Binary logistic regression was conducted to find the variables that were significantly and independently associated with knowledge, attitude and asthma management counseling practice. Results Increased years of experience was associated with decreased knowledge (OR = 0.918, 95% Cl (0.869:0.970), P = 0.002) and less positive attitude toward asthma management (OR = 0.876, 95% Cl. (0.821:0.935), P < 0.001), while working in independent community pharmacy (OR = 2.097, 95% Cl. (1.273:3.454), P = 0.004) and increased awareness of asthma management guidelines (OR = 1.60, 95% CI. (1.044:2.453), P = 0.031) increased the odds of being in the high knowledge group. In contrast, increasing the daily number of pharmacy visitors OR = 1.009, 95% Cl. (1.001:1.016), P = 0.024) and having a pharmacy degree (OR = 2.330, 95% Cl. (1.256:4.326), P = 0.007) increased the odds of having a positive attitude. Male pharmacists (OR = 0.553, 95% Cl. (0.350:0.873), P = 0.011) and having bachelor in pharmacy (OR = 0.354, 95% Cl. (0.179:0.700), P = 0.003) decreased the odds of being in the high practice group. On the other hand, increased awareness of asthma management guidelines tripled the odds of being in the high practice group (OR = 3.067, 95% Cl. (1.964:4.787), P < 0.001). Conclusion The current study findings offer valuable insights into the gaps in knowledge, attitude, and practice of asthma management counseling among community pharmacists, as well as the barriers and factors that impede the provision of these services. These insights serve as a guide for developing future strategies aimed at enhancing the role of pharmacists in asthma care.

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Section: Introductionmentioning

confidence: 99%

Role of Community Pharmacist in Asthma Management: Knowledge, Attitudes and Practice

Jarab,

Al-Qerem,

Alzoubi

et al. 2024

JMDH

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Predictive parameters of uncontrolled asthma in the real world: a prospective study

Ayik,

Karadeniz,

Tatlı

et al. 2024

Journal of Asthma

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CRHR1 polymorphism at rs242941, rs242940, and rs72834580: association of symptoms improvement with intranasal corticosteroids in allergic rhinitis Jordanian patients

Zihlif,

Abusara,

Al-Qerem

et al. 2023

Drug Metabolism and Personalized Therapy

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Objectives Rhinitis is classified into several types with allergic rhinitis (AR) being the most common. AR is among the inflammatory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), in which corticosteroids are administered to overcome the decrease in cortisol production. The treatment options available for AR vary with 1st line treatment being intranasal corticosteroids (INCS). The responsiveness to corticosteroids is due to their binding to corticotropin-releasing hormone receptor-1 (CRHR1). Various studies have studied the responsiveness to corticosteroids treatment in patients with asthma and COPD in association with CRHR1 gene single nucleotide polymorphisms (SNPs). Methods In our study, we investigated the association of three SNPs of CRHR1 gene (rs242941, rs242940, and rs72834580) with symptoms improvement post-treatment in AR patients. Blood samples were collected from 103 patients for DNA extraction and gene sequencing. Those patients started to receive INCS for 8 weeks and their symptoms were assessed, through a questionnaire, before treatment and post-treatment to check for symptoms improvement. Results Our data showed that improvement of eye redness is significantly less following INCS treatment in patients with allele (C) (AOR=0.289, p-Value-0.028, 95 % CI=0.096–0.873) and genotype (CC) (AOR=0.048, p-Value-0.037, 95 % CI=0.003–0.832) of rs242941 SNP. There was no correlation with other genotypes, alleles, or haplotypes of the investigated SNPs. Conclusions Our findings show that there is no correlation between CRHR1 gene polymorphism and symptoms improvement following INCS treatment. Further studies are required to evaluate the association of INCS and symptoms improvement post-treatment with larger sample size.

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Variables associated with asthma control among adult patients

Cited by 3 publications

References 51 publications

Role of Community Pharmacist in Asthma Management: Knowledge, Attitudes and Practice

Role of Community Pharmacist in Asthma Management: Knowledge, Attitudes and Practice

Predictive parameters of uncontrolled asthma in the real world: a prospective study

CRHR1 polymorphism at rs242941, rs242940, and rs72834580: association of symptoms improvement with intranasal corticosteroids in allergic rhinitis Jordanian patients

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