Varying negative appendectomy rates after laparoscopic appendectomy: a systematic review and meta-analysis

Henriksen, S. D.; Christophersen, Camilla; Rosenberg, Jacob; Fonnes, Siv

doi:10.1007/s00423-023-02935-z

Cited by 9 publications

(2 citation statements)

References 94 publications

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“…A study by Jukić et al also shows a higher overall negative appendectomy rate for pediatric patients during a ten-year period [ 21 ]. The reported negative appendectomy rate varies considerably in the literature, mainly due to poorly defined inclusion criteria [ 22 ].…”

Section: Discussionmentioning

confidence: 99%

Comparison of Clinical, Pathological, and Procedural Characteristics of Adult and Pediatric Acute Appendicitis before and during the COVID-19 Pandemic

Augustin,

Žedelj,

Jeričević

et al. 2024

Children

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Background: This study aims to analyze the impact of the COVID-19 pandemic on the clinical, pathological, and surgical characteristics of acute appendicitis (AA) at the University Hospital Centre (UHC) Zagreb. Methods: This retrospective study analyzed demographic, clinical, and surgical data from consecutive AA patients. Data were collected from an electronic database for two periods: 1 January to 31 December 2019 (pre-COVID-19), and 11 March 2020, to 11 March 2021 (COVID-19 pandemic). Results: During the two study periods, 855 appendectomies were performed, 427 in the pre-pandemic, and 428 during the pandemic. Demographic data were comparable between groups. There was statistically no significant difference in the type of appendectomy (p = 0.33) and the median hospital length of stay (3; (2–5) days, p = 0.08). There was an increase in the conversion rate during the pandemic period (4.2% vs. 7.7%, p = 0.03). The negative appendectomy rate and the incidence of perforated AA did not differ significantly (p = 0.34 for both). Conclusions: We did not observe a significant increase in the rate of AA complications during the COVID-19 pandemic at the UHC Zagreb. This may be attributed to two factors: (1) AA was diagnosed and treated as an emergency, which remained available during the pandemic, and (2) diagnostic and therapeutic protocols remained unaltered. We recommend a laparoscopic approach even during the COVID-19 pandemic.

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Section: Discussionmentioning

confidence: 99%

Comparison of Clinical, Pathological, and Procedural Characteristics of Adult and Pediatric Acute Appendicitis before and during the COVID-19 Pandemic

Augustin,

Žedelj,

Jeričević

et al. 2024

Children

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“…However, appendectomy is associated with a series of complications such as wound infection, incisional hernia, intra-abdominal infection, intestinal obstruction, interstitial pneumonia, urinary tract infection, cardiovascular accidents, etc [ 11 - 13 ]. Excessive surgical treatment can also lead to negative appendectomies, with recent studies reporting rates as high as 8%-30%[ 14 , 15 ]. Studies have suggested controversy over the impact of appendectomy on the development of inflammatory bowel disease and Parkinson’s disease[ 16 , 17 ], but an increasing number of studies indicate a possible positive correlation between appendectomy and colorectal cancer, gallstones, and cardiovascular disease[ 18 - 20 ].…”

Section: Introductionmentioning

confidence: 99%

Is appendoscope a new option for the treatment of acute appendicitis?

Feng,

Zhou,

Yang

et al. 2024

World J Gastroenterol

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Acute appendicitis is a common surgical emergency. It is commonly caused by obstruction of the appendiceal lumen due to fecaliths, tumors, or lymphoid hyperplasia. For over a century, appendectomy has been the primary treatment for acute appendicitis. Abraham Groves performed the first open appendectomy in 1883. In 1983, Kurt Semm completed the first laparoscopic appendectomy, heralding a new era in appendectomy. However, appendectomy is associated with certain complications and a rate of negative appendectomies. Studies have suggested controversy over the impact of appendectomy on the development of inflammatory bowel disease and Parkinson’s disease, but an increasing number of studies indicate a possible positive correlation between appendectomy and colorectal cancer, gallstones, and cardiovascular disease. With the recognition that the appendix is not a vestigial organ and the advancement of endoscopic te-chnology, Liu proposed the endoscopic retrograde appendicitis therapy. It is an effective minimally invasive alternative for treating uncomplicated acute appendicitis. Our team has developed an appendoscope with a disposable digital imaging system operated through the biopsy channel of a colonoscope and successfully applied it in the treatment of appendicitis. This article provides an overview of the progress in endoscopic treatment for acute appendicitis and offers a new perspective on the future direction of appendiceal disease treatment.

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Time to improve the management of patients with suspected acute appendicitis: a retrospective study

Paisant,

Faroche,

Fouche

et al. 2024

Abdom Radiol

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Varying negative appendectomy rates after laparoscopic appendectomy: a systematic review and meta-analysis

Cited by 9 publications

References 94 publications

Comparison of Clinical, Pathological, and Procedural Characteristics of Adult and Pediatric Acute Appendicitis before and during the COVID-19 Pandemic

Comparison of Clinical, Pathological, and Procedural Characteristics of Adult and Pediatric Acute Appendicitis before and during the COVID-19 Pandemic

Is appendoscope a new option for the treatment of acute appendicitis?

Time to improve the management of patients with suspected acute appendicitis: a retrospective study

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