“…Autologous sources for soft tissue augmentation have been sought by physicians, especially in the field of aesthetic medicine due to the possible transient effects associated with foreign materials including the possibility of granuloma formation and chronic or delayed infections caused by biodegradable foreign substances. 24 Furthermore, exogenous autologous growth factor safety, especially in relation to cancer, has not been established. As a result, autologous platelets products containing growth factors such as platelet-derived growth factor (PDGF), transforming-growth factor (TGF, especially TGF-b), vascular endothelial growth factor (VEGF), insulin-like growth factor (IGF), and epidermal growth factor (EGF), have been studied extensively over the last decade.…”