Vascular stents

Mattos, Mark A.; Hodgson, Kim J.; Hurlbert, Scott N.; Henretta, John P.; Sternbach, Yaron; Douglas, Mike G.; Mansour, M. Ashraf; Hood, Douglas B.; Sumner, David S.

doi:10.1016/s0011-3840(99)80806-5

Cited by 5 publications

(2 citation statements)

References 313 publications

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“…The basic structure of these kinds of models was similar to those described by Mattos et al. (14) and Mariano and Sangiorgi (29), which is shown in Fig. 6.…”

Section: Resultssupporting

confidence: 74%

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A New Way to Reduce Flow Disturbance in Endovascular Stents: A Numerical Study

et al. 2011

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Traditional commercial stents are made of wires with square or semi-circular cross-sections that lead to flow disturbance, which plays an important role in the initiation and progression of restenosis. A new stent with streamlined cross-sectional wires was proposed and researched numerically for its hemodynamic performance. Simplified models of stents with square, semi-circular, or streamlined cross-sectional wires were constructed numerically. Blood flows in the three models were simulated using computational fluid dynamics methods, and compared in terms of flow pattern, wall shear stress (WSS), and oscillating shear index (OSI). The results showed that when compared with the two traditional stents, the new stent with streamlined cross-sectional wires induced almost no flow disturbance, significantly enhanced WSS, and reduced the value of OSI within the stent. The present preliminary study indicates that the optimization of the cross-sectional shape of stent wires ought to be considered in the structural design for endovascular stents.

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“…The basic structure of these kinds of models was similar to those described by Mattos et al. (14) and Mariano and Sangiorgi (29), which is shown in Fig. 6.…”

Section: Resultssupporting

confidence: 74%

“…Traditional commercial stents are made of wires with square or semi‐circular cross‐sections (13,14), which always produce disturbed flow zones with low WSS and high OSI in the vicinity of the stent wires. Aquatic animals such as fish have streamlined body structures, which can reduce water resistance and allow them to swim faster.…”

mentioning

confidence: 99%

A New Way to Reduce Flow Disturbance in Endovascular Stents: A Numerical Study

et al. 2011

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Materials, fluid dynamics, and solid mechanics aspects of coronary artery stents: A state‐of‐the‐art review

Lewis

2008

J Biomed Mater Res

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It is well known that, across all populations (based on geographic location, race, ethnicity, age, and sex), coronary artery disease (CAD) is the single most common cause of death. The commonly performed revascularization procedures for the treatment of symptomatic CAD are percutaneous transluminal coronary angioplasty (PTCA) by itself or followed by the deployment of either a bare-metal stent (BMS) or a drug-eluting stent (DES). In the latter type, a drug that is either embedded in polymeric or nonpolymeric coating(s) on the stent surface or directly attached to the stent surface elutes into the blood stream at a controlled rate over a period of time, typically 14-30 days. Over the years, there has been a steady decline in the use of PTCA and a concomitant sharp increase in the use of stents, with DESs being the predominant choice in the last 3 years. The present contribution represents a critical review of the literature on the materials, fluid dynamics, and solid mechanics aspects of both BMSs and DESs, with special reference to in-stent restenosis and in-stent thrombosis, these being risks that present commonly.

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