Vasculotoxic snake bite presenting with sepsis, acute renal failure, disseminated intravascular coagulation, and acute respiratory distress syndrome

Vikhe, Vikram Bhausaheb; Gupta, Ankur; Shende, Prakash; Jain, Jinendra

doi:10.4103/0975-2870.110314

Cited by 5 publications

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“…The snakebite is considered to be an occupational hazard, especially for agriculture labourers/farm workers 4 and snake handlers. The haemotoxic snakebites usually lead to the development of disseminated intravascular coagulation (DIC), renal failure, intravascular haemolysis and acute respiratory disease syndrome (ARDS) 5 6 . Acute renal damage is common cause of morbidity and mortality in most Indian patients with Russell's Viper bites 7 .…”

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confidence: 99%

Incidence & prognosis of acute kidney injury in individuals of snakebite in a tertiary care hospital in India

Pulimaddi

Parveda

Brahmanpally

et al. 2017

Indian Journal of Medical Research

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Background & objectives:The snakebites are considered to be an occupational hazard in agriculture workers and the snake handlers, resulting in a considerable morbidity, mortality and economical implications. This study was conducted to determine the incidence, clinical presentation, renal injury and clinical outcome in snakebite victims who developed acute kidney injury (AKI).Methods:This hospital-based prospective, observational study was done on 100 cases who were admitted for the management of snakebite and found to develop AKI in a tertiary care hospital at Hyderabad, India. Renal function tests, complete blood picture, urine routine examination, ultrasound examination of abdomen and coagulation profile were done and the prognosis was assessed by noting recovery, mortality, morbidity and/or progress to chronic stage.Results:A total of 100 patients with a mean age of 43.80±12.63 yr (range 18-70); 62 males and 38 females were studied. All had bites on lower limbs. A total of 86 patients arrived in the hospital within 24 h, and 14 arrived after 24 h. Oliguria was found in 60, bleeding tendencies in 64, haemodynamic instability noted - tachycardia in 86. Systolic blood pressure (BP) was <120 mm Hg in 68 and BP was not recordable in four patients. Twelve patients were in stage III kidney disease and needed haemodialysis. Of the 100 cases of snakebite-induced acute kidney failure, 86 recovered and six died. On follow up, after six months eight patients developed chronic kidney failure.Interpretation & conclusions:A cascade of events tends to occur in severe haemotoxic envenomation such as bleeding disorders, hypotension/circulatory shock, intravascular haemolysis, disseminated intravascular coagulation and acute respiratory disease syndrome (ARDS). The findings of this study showed that early hospitalization, quick antisnake venom administration and adequate supporting care provided promising results.

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confidence: 99%

Incidence & prognosis of acute kidney injury in individuals of snakebite in a tertiary care hospital in India

Pulimaddi

Parveda

Brahmanpally

et al. 2017

Indian Journal of Medical Research

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“…Increased vascular permeability causes peripheral pooling of blood resulting in decreased perfusion of renal circulation. 1 The purpose of describing these two cases is to depict that delay in starting of AVS therapy in our first case results in a devastating outcome. We have got the patient after 72 hours of the bite.…”

Section: Discussionmentioning

confidence: 99%

“…Approximately 45,900 are reported to be fatal in a year. 1 A previous community-based survey in the state revealed that only 22% snake bite victims attended hospitals. 2 Apart from systemic effect snake envenomation has some local tissue destroying action also.…”

Section: Introductionmentioning

confidence: 99%

Two cases of viper bite: still an important health problem

Hajra

Bandyopadhyay

2016

Int J Res Med Sci

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“…Outcomes are worse as majority of the affected population is from rural areas and delay in seeking early medical care facilities. Some snake bites can lead to serious local and systemic manifestations like cellulitis, necrosis, acute renal failure, and haemorrhagic manifestations [4]. Early intervention plays a major role in these cases to improve the outcome.…”

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confidence: 99%

Symmetrical Peripheral Gangrene Post Snake-Bite: An Unusual Presentation

Jaiswal

Payagude

Upganlawa

et al. 2017

IJCR

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Snake bite in India is a common yet neglected public health issue, with an estimated death rate of 50,000 per year. Symmetrical peripheral gangrene (SPG) has varied aetiology, but it is an unusual complication after snake bites. SPG is important as it causes significant morbidity and mortality, and early intervention may improve the outcome. Hereby, we report a case of SPG in young female with history of snake bite. The patient developed gangrene of bilateral foot and distal part of legs with necrotising fasciitis of right leg. In the literature, there are only few reported cases of SPG as a complication of snake bite.

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Vasculotoxic snake bite presenting with sepsis, acute renal failure, disseminated intravascular coagulation, and acute respiratory distress syndrome

Cited by 5 publications

References 0 publications

Incidence & prognosis of acute kidney injury in individuals of snakebite in a tertiary care hospital in India

Incidence & prognosis of acute kidney injury in individuals of snakebite in a tertiary care hospital in India

Two cases of viper bite: still an important health problem

Symmetrical Peripheral Gangrene Post Snake-Bite: An Unusual Presentation

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