2019
DOI: 10.1111/cei.13259
|View full text |Cite
|
Sign up to set email alerts
|

Vasoactive intestinal peptide is required in the maintenance of immune regulatory competency of immune regulatory monocytes

Abstract: Dysfunction of the immune regulatory system plays an important role in the pathogenesis of rheumatoid arthritis (RA). Vasoactive intestinal peptide (VIP) has multiple bioactivities. This study aims to investigate the role of VIP in the maintenance of the immune regulatory capacity of monocytes (Mos). Human peripheral blood samples were collected from RA patients and healthy control (HC) subjects. Mos and CD14 + CD71 -CD73 + CD25 + regulatory Mos (RegMos) were isolated from the blood samples and characterized b… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1

Citation Types

0
1
0

Year Published

2019
2019
2019
2019

Publication Types

Select...
2

Relationship

0
2

Authors

Journals

citations
Cited by 2 publications
(1 citation statement)
references
References 35 publications
0
1
0
Order By: Relevance
“…VPAC1 expression is shown to be downregulated in synovial tissue of CIA rats and is enhanced by electroacupuncture treatment while VPAC2 remains the same (51). In the most recent paper published thus far, the authors hypothesized that VIP downregulates the CIA rat model by virtue of the enrichment of regulatory monocytes (52).…”
Section: Vip/vpac Axis In Animal Models Of Rheumatoid Arthritismentioning
confidence: 99%
“…VPAC1 expression is shown to be downregulated in synovial tissue of CIA rats and is enhanced by electroacupuncture treatment while VPAC2 remains the same (51). In the most recent paper published thus far, the authors hypothesized that VIP downregulates the CIA rat model by virtue of the enrichment of regulatory monocytes (52).…”
Section: Vip/vpac Axis In Animal Models Of Rheumatoid Arthritismentioning
confidence: 99%