Vasorreactividad a adenosina en los pacientes con hipertensión pulmonar arterial: Prevalencia y respuesta clínica, funcional y hemodinámica al tratamiento con diltiazem

Abstract

Acute vasodilatador test using adenosine in patients with pulmonary arterial hypertension: Prevalence and clinical, functional and hemodynamic response after diltiazem treatment Pulmonary arterial hypertension (PAH) is a severe and progressive disease. Invasive hemodynamic study (HS) is required to confirm the diagnosis of PAH and to perform the vasodilator test (VT) with adenosine. Vasodilator acute responders (VAR) may have a sustained benefit with diltiazem. There is not national information regarding these issues. All patients with probable PAH were evaluated with HS and VT. VAR were treated with diltiazem and followed up with functional class score (FC) and 6 minute walk test. After 6 months, a second HS was performed.