Vectorial theory surpasses the local theory in explaining the origin of P-wave dispersion

Puerta, Raimundo Carmona; Martínez, Elizabeth Lorenzo; López-Calleja, Magdalina Rabassa; Peña, Gustavo Padrón; Elizundia, Juan Miguel Cruz; González, Fernando Rodríguez; González, Elibet Chávez

doi:10.1016/j.jelectrocard.2021.04.015

Cited by 4 publications

(16 citation statements)

References 18 publications

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“…3,5 PWD appears as a consequence of the standardization of the 12-lead electrocardiogram (25 mm/s -10 mm/mV or 50 mm/s -20 mm/mV) and disappear when using magnification software. 3 Why does PWD continue to be a predictor parameter in clinical studies? A strong correlation between Pmax and PWD has been well described and it was later ratified.…”

Section: P-wave Dispersion Is a Vectorial Phenomenon: Is It Time To C...mentioning

confidence: 99%

“…And both the local and vector theories explain the phenomenon when there are conduction disturbances, but the vector theory explains it with more strength. 3,5 Certainly, there are limitations to PWD with the limited spatial resolution and the specified 12-lead ECG, but there may be a future for PWD with improved spatial resolution and using other than usual 12-lead ECG, such as mechanical analysis or rather than 12-lead ECG. A change of mind is necessary and there is scientific evidence for it.…”

Section: P-wave Dispersion Is a Vectorial Phenomenon: Is It Time To C...mentioning

confidence: 99%

“…In addition, it was found that PWD tends to dissipate when P wave is magnifyed(magnified) from 10× to 160×. After magnification, PWD was reduced from 48 to 4 ms. 3 …”

mentioning

confidence: 99%

“… 3 , 5 PWD appears as a consequence of the standardization of the 12‐lead electrocardiogram (25 mm/s ‐ 10 mm/mV or 50 mm/s ‐ 20 mm/mV) and disappear when using magnification software. 3 …”

mentioning

confidence: 99%

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P‐wave dispersion is a vectorial phenomenon: Is it time to change minds?

Puerta¹,

Martínez

Donoiu

et al. 2022

Journal of Arrhythmia

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Section: P-wave Dispersion Is a Vectorial Phenomenon: Is It Time To C...mentioning

confidence: 99%

Section: P-wave Dispersion Is a Vectorial Phenomenon: Is It Time To C...mentioning

confidence: 99%

“…In addition, it was found that PWD tends to dissipate when P wave is magnifyed(magnified) from 10× to 160×. After magnification, PWD was reduced from 48 to 4 ms. 3 …”

mentioning

confidence: 99%

mentioning

confidence: 99%

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P‐wave dispersion is a vectorial phenomenon: Is it time to change minds?

Puerta¹,

Martínez

Donoiu

et al. 2022

Journal of Arrhythmia

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“…P‐Wave Dispersion (PWD) is a non‐invasive parameter defined as the difference between the longest and the shortest P‐Wave duration on the surface electrocardiogram (ECG), 1 , 2 which has been investigated in atrial fibrillation (AF), hypertension, and stroke. 3 , 4 , 5 , 6 …”

Section: Introductionmentioning

confidence: 99%

Global cognitive function correlates with P‐wave dispersion in frail hypertensive older adults

Mone

Pansini

Calabrò

et al. 2022

J of Clinical Hypertension

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P-Wave Dispersion (PWD) is an ECG parameter defined as the difference between the longest and the shortest P-Wave duration. PWD has been associated with hypertension, a leading cause of age-related cognitive decline. Moreover, hypertension is associated with vascular dementia and Alzheimer's Disease. Based on these considerations, we evaluated PWD and global cognitive function in frail hypertensive older adults with a previous diagnosis of cognitive decline. We evaluated consecutive frail hypertensive patients ≥65-year-old with a Mini-Mental State Examination (MMSE) score <26. Patients with evidence of secondary hypertension, history of stroke, myocardial infarction, or therapy with beta-blockers or acetylcholinesterase inhibitors were excluded. Beta-blocker therapy causes a significant decrease in PWD; patients treated with acetylcholinesterase inhibitors were not included to avoid confounding effects on cognitive function. By examining 180 patients, we found that PWD significantly correlated with MMSE score. Strikingly, these effects were confirmed in a linear multivariate analysis with a regression model. To our knowledge, this is the first study showing that PWD correlates with global cognitive function in frail hypertensive older adults.

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