Vegetative pyoderma gangrenosum: a report of two new cases and a review of the literature

Langan, Sinéad; Powell, Frank C.

doi:10.1111/j.1365-4632.2005.02591.x

Cited by 32 publications

(20 citation statements)

References 26 publications

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“…The vegetative variant is a superficial painless ulcer with undermined edges. It slowly enlarges and may be exophytic with no clear pattern of specific associated disease 8. Parastomal PG presents as a non healing ulcer next to a colostomy site.…”

Section: Specific Inflammatory Conditionsmentioning

confidence: 99%

Unusual Causes of Cutaneous Ulceration

Panuncialman

Falanga

2010

Surgical Clinics of North America

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Synopsis Skin ulceration is a major source of morbidity and is often difficult to manage. Ulcers due to an inflammatory etiology or microvascular occlusion are particularly challenging in terms of diagnosis and treatment. The management of such ulcers requires careful assessment of associated systemic conditions and a thorough analysis of the ulcer's clinical and histologic findings. In this report, we discuss several examples of inflammatory ulcers and the approach to their diagnosis and treatment.

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Section: Specific Inflammatory Conditionsmentioning

confidence: 99%

Unusual Causes of Cutaneous Ulceration

Panuncialman

Falanga

2010

Surgical Clinics of North America

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“…Histopathology reveals neutrophilic abscesses, chronic inflammatory infiltrate of giant cells, plasma cells and eosinophils, palisading granulomatous reaction, and sinus formation. [67] Cutaneous tuberculosis and metastatic Crohn's disease may present with genital ulcers with granulomatous histology and needs to be ruled out. [8] Pathergy phenomenon which refers to localization of PG lesions at site of trauma is rare in the vegetative type.…”

Section: Discussionmentioning

confidence: 99%

“…Other treatment options are systemic corticosteroids, dapsone, clofazimine, thalidomide, topical sodium cromoglycate, and cyclosporine. [6910]…”

Section: Discussionmentioning

confidence: 99%

Granulomatous pyoderma gangrenosum of the genitalia in the absence of Crohn′s disease

Kambil

Bhat

Dandekeri

2015

Indian J Sex Transm Dis

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Pyoderma gangrenosum (PG) is a rare ulcerative neutrophilic disorder of the skin. Atypical variants of PG such as vegetative PG, bullous PG, and pustular forms are described in literature. Occasionally, granulomatous reaction in dermis may be seen on histology when PG is associated with Crohn's disease or in the vegetative variant of PG. We report a case of granulomatous PG involving the genitalia in a 43-year-old female without associated inflammatory bowel disease.

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“…Two more Japanese case reports can be found. In addition, cases with underlying paraproteinemia, chronic renal failure, rheumatoid arthritis, Behçet's disease, osteomyelitis, and chronic lymphocytic leukemia have been reported in the literature . Despite the fact that tetracyclines are regarded to be sufficient treatment option of superficial granulomatous pyoderma, in the presented patient previous short‐term therapy with doxycycline failed to suppress the disease.…”

mentioning

confidence: 88%

“…Superficial granulomatous pyoderma is considered to be a very rare, vegetative variant of pyoderma gangrenosum (PG). Less than 80 cases have been reported to date . Clinically, it is characterized by superficial vegetative ulcerations of a prolonged, rather benign course.…”

mentioning

confidence: 99%