This special issue comprises a selected set of high‐quality and extended articles of the 28th Systems, Software and Services Process Improvement (EuroSPI) Conference, held in 2021 in Krems, Austria.Conferences were held in Dublin (Ireland) in 1994, in Vienna (Austria) in 1995, in Brighton (UK) in 1996, in Budapest (Hungary) in 1997, in Gothenburg (Sweden) in 1998, in Pori (Finland) in 1999, in Copenhagen (Denmark) in 2000, in Limerick (Ireland) in 2001, in Nuremberg (Germany) in 2002, in Graz (Austria) in 2003, in Trondheim (Norway) in 2004, in Budapest (Hungary) in 2005, in Joensuu (Finland) in 2006, in Potsdam (Germany) in 2007, in Dublin (Ireland) in 2008, in Alcala (Spain) in 2009, in Grenoble (France) in 2010, in Roskilde (Denmark) in 2011, in Vienna (Austria) in 2012, in Dundalk (Ireland) in 2013, in Luxembourg in 2014, in Ankara (Turkey) in 2015, in Graz (Austria) in 2016, in Ostrava (Czech Republic) in 2017, in Bilbao (Spain) in 2018, in Edinburgh (UK) in 2019, in Düsseldorf (Germany) in 2020, and in Krems (Austria) in 2021.