Venous leg ulcer management: single use negative pressure wound therapy

Dowsett, Caroline; Grothier, Lorraine; Henderson, Valerie C.; Leak, Kathy; Milne, Jeanette; Davis, Lynn; Bielby, Alistair; Timmons, John

doi:10.12968/bjcn.2013.18.sup6.s6

Cited by 7 publications

(5 citation statements)

References 9 publications

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“…Efficacy comparable to that of conventional electrical NPWT (V.A.C™) has been demonstrated in a recent multi-centered trial ( 55 ). Portable NPWT devices including SNaP, however, are all limited in their usage as they are only suited with low-to-moderate exudate levels restricting their use in large diabetic foot wounds ( 56 , 57 ).…”

Section: New Developments and Adjunctsmentioning

confidence: 99%

Negative-pressure wound therapy for management of diabetic foot wounds: a review of the mechanism of action, clinical applications, and recent developments

Hasan

Teo

Nather

2015

Diabetic Foot & Ankle

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Negative-pressure wound therapy (NPWT) plays an important role in the treatment of complex wounds. Its effect on limb salvage in the management of the diabetic foot is well described in the literature. However, a successful outcome in this subgroup of diabetic patients requires a multidisciplinary approach with careful patient selection, appropriate surgical debridement, targeted antibiotic therapy, and optimization of healing markers. Evolving NPWT technology including instillation therapy, nanocrystalline adjuncts, and portable systems can further improve results if used with correct indications. This review article summarizes current knowledge about the role of NPWT in the management of the diabetic foot and its mode of action, clinical applications, and recent developments.

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Section: New Developments and Adjunctsmentioning

confidence: 99%

Negative-pressure wound therapy for management of diabetic foot wounds: a review of the mechanism of action, clinical applications, and recent developments

Hasan

Teo

Nather

2015

Diabetic Foot & Ankle

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“…It is a consensus that suNPWT is able to enhance the healing of open wounds as well as of closed (surgical) incisions, and thereby, reduce the cost of wound care, 12 , 51 , 52 , 53 , 54 , 55 , 56 however, suNPWT systems are not all the same. It is therefore imperative to understand the different modes of action of commercially available suNPWT technologies and systems, and their resulting performance metrics, primarily with respect to the CB versus CL design concepts, but also regarding the mechanobiological effects of the magnitude of the intended negative pressure.…”

Section: Discussionmentioning

confidence: 99%

Effective negative pressure wound therapy for open wounds: The importance of consistent pressure delivery

Orlov

Gefen

2022

International Wound Journal

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Two distinct design concepts exist for single‐use negative pressure wound therapy systems: Canister‐based versus canisterless. The canister‐based technology provides intrinsic stable delivery of the intended negative pressure, because exudate is constantly transferred from the wound into a canister, thereby preventing dressing saturation. In contrast, with a canisterless system, where delivery of the negative pressure depends on continuous evaporation of wound fluids from its dressing, loss of the intended wound‐bed pressure may occur due to dressing saturation. To investigate whether these two designs differ in their mechanobiological effect with respect to magnitudes and distributions of tissue strain fields under the absorptive dressing, termed the influence zone, we integrated computational modelling with an animal study. This influence zone must be of biologically influential strain levels and extend sufficiently into the peri‐wound for stimulating fibroblasts to migrate and progress the healing. We found that an effective influence zone requires continuous delivery of the intended pressure to the wound‐bed. Loss of negative pressure at the wound‐bed below 40 mmHg adversely lowered the peri‐wound stimulation around a 120 × 70 mm sized wound to less than one‐third of the baseline stimulation, and further pressure decreases to 20 mmHg or lower resulted in complete lack of peri‐wound mechano‐stimulation.

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“…Exsudate can be removed and the wound cleaning can be promoted. NPWT is indicated for leg ulcers, deep pressure ulcers, traumatic wounds and to support post-surgical supply of skin grafts (35,36). While randomized controlled-trials for NPWT are missing a number of positive case series are proving the effect of this therapy.…”

Section: Debridement and Antimicrobial Effectsmentioning

confidence: 99%