Venous thromboembolism — recommendations on the prevention, diagnostic approach and management. The 2017 Polish Consensus Statement

Tomkowski, Witold; Kuca, Paweł; Urbanek, Tomasz; Chmielewski, Dariusz; Krasiński, Zbigniew; Pruszczyk, Piotr; Windyga, Jerzy; Oszkinis, Grzegorz; Jawień, Arkadiusz; Burakowski, Janusz; Dybowska, Małgorzata; Kęsik, Jan; Zubilewicz, Tomasz

doi:10.5603/aa.2017.0008

Cited by 17 publications

(40 citation statements)

References 59 publications

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“…Scientific evidence regarding the effectiveness and excellent safety profile of sulodexide in the prophylaxis (therapy) of deep vein thrombosis (DVT) recurrence is solid and translated into recommendations contained in the Polish guidelines [9][10][11][12].…”

Section: Effectiveness and Safety Of Sulodexide In The Prevention Of mentioning

confidence: 99%

“…The treatment of DVT consists of three phases: acute treatment phase, usually lasting 5-7 days (in patients treated with rivaroxaban this phase lasted 21 days), long-term anticoagulation therapy lasting 3 months, and chronic prophylaxis (therapy) of DVT recurrence, which lasts from several months to years, and may be indefinite in some patients [12].…”

Section: Effectiveness and Safety Of Sulodexide In The Prevention Of mentioning

confidence: 99%

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Effectiveness and safety of sulodexide in the treatment of venous diseases

Tomkowski

Dybowska

2019

Acta Angiologica

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This article presents a review of the literature assessing the effectiveness and safety of sulodexide in the prophylaxis of deep vein thrombosis and treatment of chronic venous disease. It was demonstrated that sulodexide is effective and safe in the prophylaxis of deep vein thrombosis and treatment of chronic venous insufficiency with ulcers. Sulodexide is characterized by low frequency of bleeding complications.

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Section: Effectiveness and Safety Of Sulodexide In The Prevention Of mentioning

confidence: 99%

Section: Effectiveness and Safety Of Sulodexide In The Prevention Of mentioning

confidence: 99%

Effectiveness and safety of sulodexide in the treatment of venous diseases

Tomkowski

Dybowska

2019

Acta Angiologica

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“…Although these factors are crucial, they are not the only ones responsible for VTE. It is a well-known fact that immobility, surgeries, bacteraemia, pregnancy, the postpartum period, hormone therapy, varices, dehydration, obesity, age over 40 and thrombophilia are also further risks of VTE [4]. Other studies also add cancer history, inflammatory bowel disease, rheumatic diseases, heart failure, injury, surgery and transfusions of RBC [5].…”

Section: Brief State Of Knowledgementioning

confidence: 99%

“…Adding mechanical methods can improve the effectiveness of pharmacological treatment, and is most useful in patients with a high risk of VTE. Patients with haemorrhage and with contraindications to pharmacological prophylaxis can be treated only with mechanical methods [4,5,11].…”

Section: Thromboprophylaxis In Particular Types Of Traumasmentioning

confidence: 99%

“…According to Tomkowski and Witold, et al, using LMWH is a class A recommendation, while UFH and fondaparinux belong to class B recommendation. Applying mechanical thromboprophylaxis, such as antiembolism stockings (AES), foot impulsed technology (FIT), intermittent pneumatic compression (IPC) should be considered when there are contraindications to using pharmacological TPX (B class recommendation) [4]. If an immediate surgical treatment is not possible, pharmacological or mechanical TPX should be applied as soon as a fracture is diagnosed.…”

Section: Thromboprophylaxis In Particular Types Of Traumasmentioning

confidence: 99%

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Advances in thromboprophylaxis in trauma patients, based on current guidelines and research

Grodzicki¹,

Flis²,

Sławiński³

et al. 2018

Med Og Nauk Zdr.

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Introduction. Thromboprophylaxis remains a significant element in the operative and non-operative treatment of trauma patients due to high risk of thromboembolic incidents. This problem concerns a major part of trauma patients. Objective. The aim of the study is to review and evaluate the efficacy of the pharmacological and non-pharmacological methods of venous thromboembolic (VTE) prophylaxis. Brief state of knowledge. There are a few pharmacological methods of VTE prevention, such as: unfractionated heparin (UFH), low molecular weight heparin (LMWH), vitamin K antagonists (VKA), factor Xa inhibitors and direct thrombin Inhibitor. There are also a couple of non-pharmacological methods: intermittent pneumatic compression and graduated compression stockings. The choice of method should be guided by the type of trauma, patient's health status, and potential contraindications for other methods of prophylaxis. Methods. The authors analyzed recent guidelines and research using the most up-to-date sources. The types of traumas were categorized, and a summary compiled of the best way of VTE prophylaxis for each type of trauma. Recommended methods were also rated with the risk of VTE and haemorrhage. Conclusions. The conclusions show that there are still too few studies and the guidelines extant are unambiguous (ambiguous?). Improvment must be sought for in thromboprophylaxis and toward defining uniform guidelines. Due to the large number of surgeries in the treatment of traumas, there is a need to retain all the guidelines in one article. Every operation is connected with high risk of venous thromboembolism, therefore optimal prophylaxis is crucial.

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