Ventajas y riesgos de la utilización del antígeno prostático específico (PSA) en el área sanitaria V de Gijón (Asturias)

Piorno, F.J. Cepeda; Fresno, Manuel Rivas del; Martín, Eduardo; García, Esther Gónzalez; Fernández, Valentín Muruamendiaraz; Rodríguez, Enrique Oltra

doi:10.4321/s0004-06142005000500004

Cited by 6 publications

(3 citation statements)

References 10 publications

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“…Insofar as the trend in prostate cancer incidence is concerned, in Spain there are no specific recommendations regarding early detection of this tumour, though different studies [ 20 , 21 ] show that opportunistic use of PSA as a screening test intensified at the end of the 1990s and its use has since become very widespread. The sharp change observed in the incidence of this tumour could be connected, as in the case of breast cancer, with the early implementation of such active case searching (opportunistic practices) and a higher degree of awareness among the population and professionals alike.…”

Section: Discussionmentioning

confidence: 99%

Breast and prostate cancer: an analysis of common epidemiological features in mortality trends in Spain

2014

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BackgroundBreast cancer in women and prostate cancer are the first and second leading tumour respectively in terms of incidence world-wide. Our objective is to ascertain the similarities and differences between mortality trends in breast cancer among women and prostate cancer in Spain using age-period-cohort models, and analyse the correlation between incidence of breast and prostate cancer at cancer registries locally and world-wide.MethodsWe analysed the independent effects of age, period of death and birth cohort on mortality rates for breast cancer in women and prostate cancer in Spain across the period 1952–2011. Segmented regression analyses were performed to detect and estimate changes in period and cohort curvatures. Correlation among age-adjusted incidence rates at 246 population cancer registries world-wide was analysed for the period 2003–2007.ResultsThe mortality trend displayed common characteristics in terms of the annual number of deaths due to these tumours, their adjusted mortality rates and the change points detected in the cohort and period effects. The trend in incidence was very different to that in mortality, due to early detection and progressive improvement in survival. Correlation between the incidence rates of both tumours recorded by registries around the world proved to be a generalised phenomenon.ConclusionsThis study shows that breast cancer mortality in women and prostate cancer mortality and their trends in Spain display visible similarities in terms of the number of deaths due to these tumours, their adjusted mortality rates and the changes experienced by mortality over time. The effects of advances in the diagnosis of both tumours correspond to a decline in mortality which becomes evident after a lag of approximately eight years. Correlation between breast and prostate cancer incidence rates is very high in Spain and at registries on all continents.

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Section: Discussionmentioning

confidence: 99%

Breast and prostate cancer: an analysis of common epidemiological features in mortality trends in Spain

2014

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“…Inclusive, debe ser detectado de manera temprana para su prevención, conforme lo expresa la literatura teórica. (6,7,8,9,10,11,12,13,14,15,16,17,18,19) De esta manera, se contribuye con el cumplimiento del sexto objetivo del milenio, suscrito en la Cumbre del Mileno por los países pertenecientes a la Organización de las Naciones Unidas (20) y el primer objetivo del Plan Nacional de Desarrollo de la Secretaría Nacional para la Planificación del Desarrollo, (14) para asegurar el bienestar de la población local y nacional mediante la detección temprana, tratamiento oportuno y prevención del cáncer de próstata así como otras enfermedades relacionadas con esta afección que debe generar el fortalecimiento de los indicadores sanitarios ecuatorianos.…”

Section: Discussionunclassified

“…También, se realizaron 488 biopsias prostáticas detectándose 178 carcinomas. (10) Otro estudio realizado en México, manifestó que la edad promedio en que se diagnostica el cáncer de próstata es a los 68 años de edad, inclusive el 63 % de varones fueron diagnosticados después de los 65 años, quienes, con alguna frecuencia, pueden minimizar las relaciones sexuales debido a esta afección. (11) En Bolivia, en el 2009, se encontró un PSA superior al valor de referencia (4ng/ml) en el 20 % de los 422 pacientes con hipertrofia prostática benigna del estudio.…”

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Specific prostate antigen in adults of the urban parishes of Cuenca - Ecuador

Méndez

Vicuña

2023

Salud, Ciencia y Tecnología

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The objective of this research was to determine the values of prostate-specific antigen (PSA) in the blood serum of 1100 adults aged 40 to 80 who reside in the urban parishes of the city of Cuenca during 2018. The micro ELISA technique was used to determine PSA values, a glycoprotein secreted by the prostatic epithelium that allows sperm liquefaction and spermatozoa mobility. The results revealed that 8% of patients had values higher than 4 ng/ml, considered as the maximum limit of normality and present in prostatitis, benign prostatic hyperplasia, and prostate cancer. 50% of positive cases belonged to the age group of 70 to 80 years, finding statistical significance (p<0.05) when related to variables such as age, family history, and sexual activity, highlighting the importance of establishing periodic control of this tumor marker for early detection.

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