2012
DOI: 10.1136/bmj.e3325
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Ventilator associated pneumonia

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Cited by 223 publications
(169 citation statements)
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References 105 publications
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“…In the United States of America, there is a concern about the measures for control and prevention of VAP, evidenced by the publication of the report to err is human: building a safer health care system, which highlighted the deficiencies in the area of patient safety and revealed 98,000 deaths per year as a result of medical errors [11,12].…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…In the United States of America, there is a concern about the measures for control and prevention of VAP, evidenced by the publication of the report to err is human: building a safer health care system, which highlighted the deficiencies in the area of patient safety and revealed 98,000 deaths per year as a result of medical errors [11,12].…”
Section: Discussionmentioning
confidence: 99%
“…Impairment of mucociliary clearance of secretions with gravity dependence of mucus flow within the airways. Pathogenic material can also collect in surrounding anatomic structures, such as the stomach, sinuses, nasopharynx and oropharynx, with replacement of normal flora by more virulent strains [11][12][13][14].…”
Section: Pathogenesismentioning
confidence: 99%
“…Одновременно с проведением системной терапии при различных формах синусита обязательно осуществляется местное воздействие на слизистую оболочку поло-сти носа и пазух с применением местных антисеп-тиков, а также параллельная санация ротоглотки. При этом сокращается время болезни, уменьшает-ся среднее количество пункций верхнечелюстных пазух, снижается потребность в сосудосуживаю-щих и антигистаминных средствах, что указывает на необходимость поиска наиболее оптимального антисептического препарата [12], соответствующе-го целому ряду требований: эффективность, без-опасность, широкий спектр действия, минималь-ные побочные эффекты и относительно низкая стоимость. На современном фармацевтическом рынке в качестве местного антисептика широко распространен хлоргексидин и хлоргексидинсо-держащие препараты, такие как гексикон, антиан-гин, дрилл, гексорал и т.д.…”
Section: оригинальные исследования / Original Researchesunclassified
“…It is the second most common nosocomial infection in the intensive care unit (ICU) and the most common in mechanically ventilated patients 5,6,7 . VAP rates range from 1.2 to 8.5 per 1,000 ventilator days and are reliant on the definition used for diagnosis .…”
Section: Introductionmentioning
confidence: 99%
“…Early onset VAP is defined as pneumonia that occurs within 5 days and this is usually attributed to antibiotic sensitive pathogens whereas late onset VAP is more likely caused by multidrug resistant (MDR) bacteria and emerges after 5 days of intubation 6,8 .…”
Section: Introductionmentioning
confidence: 99%