Ventricular Septal Defects

Minette, Mary S.; Sahn, David J.

doi:10.1161/circulationaha.106.618124

Cited by 313 publications

(139 citation statements)

References 40 publications

Supporting

Mentioning

122

Contrasting

Unclassified

Order By: Relevance

“…1,2 The outcome for VSD is usually excellent, and almost all patients are expected to reach childbearing age. 3,4 Despite the fact that a VSD is one of the most common forms of heart disease among pregnant women, VSD-specific pregnancy data are limited.…”

Section: Introductionmentioning

confidence: 99%

Pregnancy outcome in women with repaired versus unrepaired isolated ventricular septal defect

Yap

Drenthen

Pieper

et al. 2010

BJOG

View full text Add to dashboard Cite

Objective To compare the risks of pregnancy complications in women with repaired and unrepaired isolated ventricular septal defect (VSD).Design A retrospective multicentre study.Setting Tertiary centres in the Netherlands and Belgium.Methods Women were identified using two congenital heart disease registries. Eighty-eight women were identified who had experienced 202 pregnancies, including 46 miscarriages and nine terminations of pregnancy. Information on each completed pregnancy (n = 147; unrepaired VSD, n = 104; repaired VSD, n = 43) was obtained using medical records and telephone interviews. Data from the Generation R database (prospective cohort study; n = 9667) were used to determine the background risk (controls). Odds ratios and 95% CI were estimated using general estimation equation analysis adjusted for multiple pregnancies per woman, maternal age and parity status.Main outcome measures Adjusted odds ratios (AORs) for developing pregnancy complications in relation to corrective status.Results Pregnancies in women with an unrepaired VSD were associated with a higher risk of pre-eclampsia (AOR 4.59, 95% CI 2.01-10.5, P < 0.001) compared with controls. No differences were observed when comparing women with repaired VSD and controls. Pregnancies in women with repaired VSD were associated with a higher risk of premature labour (AOR 4.02, 95% CI 1.12-14.4, P = 0.03) and small-for-gestational-age (SGA) births (AOR 4.09, 95% CI 1.27-13.2, P = 0.02) compared with women with unrepaired VSD.Conclusions Women with unrepaired VSD are at increased risk of pre-eclampsia, which suggests that it is not a benign condition. In addition, women with repaired VSD are at increased risk of premature labour and SGA births compared with women with unrepaired VSD.

show abstract

Section: Introductionmentioning

confidence: 99%

Pregnancy outcome in women with repaired versus unrepaired isolated ventricular septal defect

Yap

Drenthen

Pieper

et al. 2010

BJOG

View full text Add to dashboard Cite

show abstract

“…Среди беременных с ИЭ, не прооперированных по поводу ВПС, наиболее часто выявляется ДМЖП [19] -его обнаруживают у 8,8-14,3% беременных [15,20], что значительно превышает распространенность этого поро-ка в общей популяции (0,3 случая на 1000 человек) [21].…”

Section: эпидемиология и предрасполагающие факторыunclassified

Infective endocarditis in pregnant women

Ватутин¹,

Тарадин²,

Chaus³

2016

Ross. vestn. akush.-ginekol.

View full text Add to dashboard Cite

“…16 The defects vary in size and are localized immediately adjacent to Most perimembranous defects are closed through the tricuspid valve using a right atrial approach that enables the surgeon, in most cases, to visualize the defect when lifting the septal leaflet of the tricuspid valve. [17][18][19][20] However, residual defects and compromise of the tricuspid valve function have been described in the postoperative period; complications that potentially can be avoided if further information about the size and extension of the defect or tricuspid valve attachments in relation to the defect could be provided in the presurgical planning.…”

Section: Insights From 3de Useful For Perimembranous Vsd Closurementioning

confidence: 99%