Versatile polyphenolic platforms in regulating cell biology

Abstract

This review summarizes the recent advances in biointerfacial engineering using polyphenolic platforms, highlighting the relationship between material properties and cell biology regulation via cell–material contact and non-contact modes.

Applications of Electrospun Drug-Eluting Nanofibers in Wound Healing: Current and Future Perspectives

“…Very high concentrations of these gases, however, may result in pathological diseases due to the oxidation of intracellular components like proteins [ 86 ]. The responses of the cell/tissue microenvironment provide a myriad of biochemical and biophysical cues for modulating cell biology, which sheds light on tissue regeneration and disease therapies [ 87 ]. To mediate a radical attack of cells by oxidizing species, the use of metallic nanoparticles and nano-enzymes, such as gold nanoparticles and lead nanocrystals, have been recommended.…”

“…Polyphenols also have ROS scavenging and photothermal properties, making them promising candidates for the regulation of extra- and intracellular ROS levels and temperatures and ultimately influencing cell biology. Polyphenols can consequently be applied to accelerate wound healing [ 87 ]. Melanin belongs to a class of natural biomolecular pigments utilized as a theranostic antioxidant and thermal stabilizers of polymers due to their excellent free radical scavenging capabilities.…”

Functional Thermoresponsive Hydrogel Molecule to Material Design for Biomedical Applications

“…Furthermore, this review illustrates phase transformation and release kinetics in several thermosensitive hydrogel systems. The paper describes the latest progress in thermoresponsive hydrogels for biological recognition, targeted drug delivery, tissue engineering, wound healing, and other applications [ 13 , 14 , 15 ].…”

Multifunctional dual emissive fluorescent probe based on europium-doped carbon dots (Eu-TCA/NCDs) for highly selective detection of chloramphenicol, Hg2+ and Fe3+

“…10 Excess iron ions, on the other hand, can be hazardous because they increase the oxidation of lipids, proteins, and other biological components. 11,12 As a result, the development of better technologies for detecting these environmental pollutants is critical. To date, numerous analytical procedures, consisting of liquid chromatographymass spectrometry, liquid/gas chromatography-tandem mass spectrometry, fluorescence assays, electrochemical sensing, and immunoassay biosensing, 5,[13][14][15][16][17][18][19][20] have been reported in previous studies for selective detection of CAP, Hg 2+ and Fe 3+ .…”