Versatile Solid Phase Synthesis of Gold Nanoparticle Dimers Using an Asymmetric Functionalization Approach

Sardar, Rajesh; Heap, Tyler B.; Shumaker‐Parry, Jennifer S.

doi:10.1021/ja070933w

Cited by 187 publications

(187 citation statements)

References 26 publications

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“…12 However, for several applications, it would be desirable to have a controlled, wet-chemistry synthesis of superstructures. Successful wet-chemistry approaches based on self-assembly has been demonstrated, for example, with DNA-templating 13 and with several different molecular linkers [14][15][16][17][18] .…”

Section: Introductionmentioning

confidence: 99%

Covalently linked multimers of gold nanoclusters Au₁₀₂(p-MBA)₄₄and Au_∼250(p-MBA)_n

et al. 2016

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We present the synthesis, separation, and characterization of covalently-bound multimers of paramercaptobenzoic acid (p-MBA) protected gold nanoclusters. The multimers were synthesized by performing a ligand-exchange reaction of a pre-characterized Au 102 (p-MBA) 44 nanocluster with biphenyl-4,4'dithiol (BPDT). The reaction products were separated using gel electrophoresis yielding several distinct bands. The bands were analyzed by transmission electron microscopy (TEM) revealing monomer, dimer, and trimer fractions of the nanocluster. TEM analysis of dimers in combination with molecular dynamics simulations suggest that the nanoclusters are covalently bound via a disulfide bridge between BPDT molecules. The linking chemistry is not specific to Au 102 (p-MBA) 44 . The same approach yields multimers also for a larger monodisperse p-MBA-protected cluster of approximately 250 gold atoms, Au ∼250 (p-MBA) n . While the Au 102 (p-MBA) 44 is not plasmonic, the Au ∼250 (p-MBA) n nanocluster supports localized surface plasmon resonance (LSPR) at 530 nm. Multimers of the Au ∼250 (p-MBA) n exhibit additional transitions in their UV-vis spectrum at 630 nm and 810 nm, indicating the presence of hybridized LSPR modes. Well-defined structures and relatively small sizes make these systems excellent candidates for connecting ab initio theoretical studies and experimental quantum plasmonics. Moreover, our work opens new possibilities in the controlled synthesis of advanced monodisperse nanocluster superstructures. † Electronic supplementary information (ESI) available: Details of syntheses and purification; additional images of PAGE runs; mass spectrum of Au 102 ( p-MBA) 44 ; 1 H NMR spectra of clusters; TEM analysis of cluster sizes; additional TEM images; core-to-core distance and angle distributions from simulations; additional multimer size statistics; additional UV-vis spectra for Au ∼250 ( p-MBA) n multimers and aggregates. See

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Section: Introductionmentioning

confidence: 99%

Covalently linked multimers of gold nanoclusters Au₁₀₂(p-MBA)₄₄and Au_∼250(p-MBA)_n

et al. 2016

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“…Compared with these 'homo-coupling' nanoreactions, controlling stoichiometry in the 'cross-coupling' of NPs presents different and arguably greater challenges. It was only achieved through the brilliant design and pre-fabrication of NPs with anisotropic surface functionalities (for example, NP with a single DNA molecule) [17][18][19][20][21][22] .…”

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confidence: 99%

A systems approach towards the stoichiometry-controlled hetero-assembly of nanoparticles

et al. 2010

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A central theme in nanotechnology is to advance the fundamental understanding of nanoscale component assembly, thereby allowing rational structural design that may lead to materials with novel properties and functions. nanoparticles (nPs) are often regarded as 'artificial atoms', but their 'reactions' are not readily controllable. Here, we demonstrate a complete nanoreaction system whereby colloidal nPs are rationally assembled and purified. Two types of functionalized gold nPs (A and B) are bonded to give specific products AB, AB 2 , AB 3 and AB 4 . The stoichiometry control is realized by fine-tuning the charge repulsion among the B-nPs. The products are protected by a polymer, which allows their isolation in high purity. The integration of hetero-assembly, stoichiometry control, protection scheme and separation method may provide a scalable way to fabricate sophisticated nanostructures.

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“…By generating such ordered arrays, the potential for reproducible and sensitive quantitative SERS analyses exists. In addition to the development of patterned arrays (already described), there has also been a great deal of recent research into the development of isolated SERS active nanoparticle dimers 68,[88][89][90][91] and target-triggered, ordered nanoparticle aggregates. 69,[92][93][94][95] Such isolated dimers and ordered aggregates offer the potential of significantly enhanced SERS signals over individual particles or larger ordered arrays, with good reproducibility.…”

Section: Organized Structuresmentioning

confidence: 99%

“…5(f)]. 88,89 Alternatively, isolated dimeric structures have also recently been fabricated, with a high degree of precision, by a process known as on-wire lithography [OWL; see Fig. 5(g)].…”

Section: Organized Structuresmentioning

confidence: 99%

Recent advances in plasmonic nanostructures for sensing: a review

2015

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Versatile Solid Phase Synthesis of Gold Nanoparticle Dimers Using an Asymmetric Functionalization Approach

Cited by 187 publications

References 26 publications

Covalently linked multimers of gold nanoclusters Au₁₀₂(p-MBA)₄₄and Au_∼250(p-MBA)_n

Covalently linked multimers of gold nanoclusters Au₁₀₂(p-MBA)₄₄and Au_∼250(p-MBA)_n

A systems approach towards the stoichiometry-controlled hetero-assembly of nanoparticles

Recent advances in plasmonic nanostructures for sensing: a review

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Versatile Solid Phase Synthesis of Gold Nanoparticle Dimers Using an Asymmetric Functionalization Approach

Cited by 187 publications

References 26 publications

Covalently linked multimers of gold nanoclusters Au102(p-MBA)44and Au∼250(p-MBA)n

Covalently linked multimers of gold nanoclusters Au102(p-MBA)44and Au∼250(p-MBA)n

A systems approach towards the stoichiometry-controlled hetero-assembly of nanoparticles

Recent advances in plasmonic nanostructures for sensing: a review

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Covalently linked multimers of gold nanoclusters Au₁₀₂(p-MBA)₄₄and Au_∼250(p-MBA)_n

Covalently linked multimers of gold nanoclusters Au₁₀₂(p-MBA)₄₄and Au_∼250(p-MBA)_n