Very Efficient and Rapid Catalyst-free One-pot Three Component Synthesis of 2,5-Dihydro-5-imino-2-methylfuran-3,4-dicarboxylate Derivatives Under Ultrasound Irradiation

Abstract

We report a fast, efficient, and facile route for the synthesis of 2,5-dihydro-5-imino-2-methylfuran-3,4-dicarboxylate derivatives from the isocyanide, dialkyl acetylenedicarboxylate and acetic anhydride under ultrasound-assisted conditions. Utilization of easy reaction conditions, very high to excellent yields, and short reaction times makes this manipulation potentially very useful.

Ultrasound‐Assisted Expeditious Catalyst‐Free Green Approach towards Diastereoselective Synthesis of Spiro[indoline‐3,2′‐pyrido[2,1‐b][1,3]oxazine]‐3′,4′‐dicarboxylate Scaffolds

“…Dialkylacetylenedicarboxylates (DAAD) are very useful reagents for the construction of different organic frameworks and especially heterocyclic scaffolds. [37][38][39] To the best of our knowledge, this new methodology presents the first example of an ultrasound-promoted expeditious and efficient multi-component approach for the…”

“…ethanol at room temperature to afford Spiro[indoline‐3,2′‐pyrido[2,1‐ b ][1,3]oxazine]‐3′,4′‐dicarboxylate derivatives in excellent yields. Dialkylacetylenedicarboxylates (DAAD) are very useful reagents for the construction of different organic frameworks and especially heterocyclic scaffolds [37–39] . To the best of our knowledge, this new methodology presents the first example of an ultrasound‐promoted expeditious and efficient multi‐component approach for the preparation of diastereoselective Spiro[indoline‐3,2′‐pyrido[2,1‐ b ][1,3]oxazine]‐3′,4′‐dicarboxylate derivatives.…”

Achieving Different Morphologies for a Zinc(II) Coordination Polymer by Green Sonochemical Synthesis and New Precursors for the Preparation of Zinc(II)oxide

“…A physical phenomenon that occurs in the synthesis of materials by ultrasonic method is cavitation. Acoustic cavitation, which involves the formation, growth, and explosion of bubbles, can provide ideal conditions for many sonochemical phenomena in a very short time …”