Vesicular pleuritis in a case of tuberculous empyema thoracis

Proliferative and Synthetic Activity of Nerve Cells after Combined or Individual Exposure to Hypoxia and Hypercapnia

“…The increase in the mean number of NORs in nerve cells indicates enhancement of ribosomal RNA synthesis at nucleolus-forming chromosomal regions [7], which up-regulates the synthesis of neurotransmitters in neurons and structural proteins and neurotrophic factors in glial cells [4]. This process plays an important role in the mechanism of neuroprotection under conditions of ischemic damage to the nerve tissue, because activation of glial cell proliferation moderates the deleterious effects of trophic abnormalities, while elevated expression of neurotransmitters is of great reparative importance for neurons entering the paranecrotic and necrobiotic phase [9].…”

“…To this end, AgNORs kit (BioOptica) was used [7]. The number NORs in the penumbra neurons were counted in at least 5 visual fi elds at ×400.…”

The Riddle of the Sphinx: Progress in Leptomeningeal Metastasis of Non–Small Cell Lung Cancer

“…Liquid biopsy can determine the tumor burden, drug efficacy, and drug resistance of NSCLC patients by detecting circulating tumor DNA (ctDNA) in peripheral blood, CSF, and other body fluids. 67 , 68 In addition, few previous studies 69 - 72 have confirmed that ctDNA in CSF compared with peripheral blood can more accurately reflect gene mutations in intracranial metastases. Using NGS liquid biopsy technology, detecting ctDNA changes in the CSF compared with peripheral blood of LM patients can more accurately and comprehensively reflect the true gene mutation status of LM.…”