Vibrio albensis bacteremia: A case report and systematic review

Ahmed, Afif; Ali, Gawahir A.; Hassen, Sara S.; Goravey, Wael

doi:10.1016/j.idcr.2022.e01551

Cited by 3 publications

(6 citation statements)

References 36 publications

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“…The non-O1/non-O139 serogroups have been associated with extraintestinal infections such as septicemia, wound infection, skin infection, cholecystitis and meningitis despite being biochemically indistinguishable from toxigenic V. cholerae O1/O139 that causes cholera illness [26]. In recent years, the number of non-O1/non-O139 Vibrio cholerae bacteremia cases has been expanding across the globe [27][28][29][30]. Invasive infections induced by non-O1/non-O139 V. cholerae are rare yet deadly.…”

Section: Discussionmentioning

confidence: 99%

Extraintestinal survival and host immune response toVibrio cholerae

Duodu

Agyei

Adade

et al. 2022

Preprint

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Vibrio cholerae is best known to cause the deadly disease cholera. However, in recent years this bacterial pathogen has been found to invade intestinal layers and translocate into the bloodstream of humans. The aim of this study was to investigate the molecular basis of V. cholerae bacteremia. Nine (9) strains of V. cholerae; six (6) environmental strains of non-O1/non-O139 serogroup and three (3) clinical strains of O1 serogroup and El-Tor serotype were screened for survival in serum obtained from immunocompromised patients. Serum from immunocompetent individuals with no known underlying conditions were used as healthy controls. Five (5) environmental strains and one (1) clinical strain of V. cholerae were identified to survive the bactericidal action of serum. Whole genome sequence analysis revealed the cholix toxin (ChxA) and genes encoding for siderophores (FepE and EntD) as possible virulence factors used by the environmental strains to cause invasive bloodstream infection. Peripheral blood mononuclear cells (PBMCs) stimulated with V. cholerae revealed increased expression of some cytokines; IL-1β and IL-13 and the chemokine; RANTES especially among diabetics. The present study illustrates the potential survival of V. cholerae in blood, which could be aided by scavenging for iron from their host leading to severe infections.

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Section: Discussionmentioning

confidence: 99%

Extraintestinal survival and host immune response toVibrio cholerae

Duodu

Agyei

Adade

et al. 2022

Preprint

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“…Vibrio cholerae is a Gram negative bacteria generally known to cause gastroenteritis and rarely extraintestinal infections in humans [1] , [2] , [3] , [4] . According to the major somatic antigen called antigen O, this species is classified in 206 serogroups.…”

Section: Introductionmentioning

confidence: 99%

“…Even if still rare, these diseases are increasingly reported [5] . Vibrio albensis , a non-O1/non-O-139 serogroup, is rarely implicated in human infections [4] , [6] .…”

Section: Introductionmentioning

confidence: 99%

“…There is no standard antibiotic therapy for the treatment of NOVC bacteremia: choose of therapy depends on antibiogram [7] , [8] because resistance strains are emerging [9] . Third-generation cephalosporin, fluoroquinolones and tetracyclines are classically used, but macrolides are frequently an alternative therapy [10] , for a classical duration of 14 days [4] , [6] .…”

Section: Introductionmentioning

confidence: 99%

“…A total of four cases of V. albensis related infections have been described before: three cases were characterized by an uncomplicated clinical course, while the remaining one suffered a multi-organ failure (MOF) and died in hospital [4] .…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Acute gastroenteritis due to Vibrio cholerae biovar albensis infection: A case report

Stolaj,

Belfiori,

Mercuri

et al. 2023

IDCases

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Public health aspects of Vibrio spp. related to the consumption of seafood in the EU

Koutsoumanis,

Allende,

Alvarez‐Ordóñez

et al. 2024

EFS2

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Vibrio parahaemolyticus, Vibrio vulnificus and non‐O1/non‐O139 Vibrio cholerae are the Vibrio spp. of highest relevance for public health in the EU through seafood consumption. Infection with V. parahaemolyticus is associated with the haemolysins thermostable direct haemolysin (TDH) and TDH‐related haemolysin (TRH) and mainly leads to acute gastroenteritis. V. vulnificus infections can lead to sepsis and death in susceptible individuals. V. cholerae non‐O1/non‐O139 can cause mild gastroenteritis or lead to severe infections, including sepsis, in susceptible individuals. The pooled prevalence estimate in seafood is 19.6% (95% CI 13.7–27.4), 6.1% (95% CI 3.0–11.8) and 4.1% (95% CI 2.4–6.9) for V. parahaemolyticus, V. vulnificus and non‐choleragenic V. cholerae, respectively. Approximately one out of five V. parahaemolyticus‐positive samples contain pathogenic strains. A large spectrum of antimicrobial resistances, some of which are intrinsic, has been found in vibrios isolated from seafood or food‐borne infections in Europe. Genes conferring resistance to medically important antimicrobials and associated with mobile genetic elements are increasingly detected in vibrios. Temperature and salinity are the most relevant drivers for Vibrio abundance in the aquatic environment. It is anticipated that the occurrence and levels of the relevant Vibrio spp. in seafood will increase in response to coastal warming and extreme weather events, especially in low‐salinity/brackish waters. While some measures, like high‐pressure processing, irradiation or depuration reduce the levels of Vibrio spp. in seafood, maintaining the cold chain is important to prevent their growth. Available risk assessments addressed V. parahaemolyticus in various types of seafood and V. vulnificus in raw oysters and octopus. A quantitative microbiological risk assessment relevant in an EU context would be V. parahaemolyticus in bivalve molluscs (oysters), evaluating the effect of mitigations, especially in a climate change scenario. Knowledge gaps related to Vibrio spp. in seafood and aquatic environments are identified and future research needs are prioritised.

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Vibrio albensis bacteremia: A case report and systematic review

Cited by 3 publications

References 36 publications

Extraintestinal survival and host immune response toVibrio cholerae

Extraintestinal survival and host immune response toVibrio cholerae

Acute gastroenteritis due to Vibrio cholerae biovar albensis infection: A case report

Public health aspects of Vibrio spp. related to the consumption of seafood in the EU

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