Viral Suppression Levels in Men Who Have Sex With Men and Transgender Women With Newly Diagnosed HIV and Alcohol Use Disorder in Peru: Results From a Randomized, Double-Blind, Placebo-Controlled Trial Using Oral Naltrexone

Gonzáles, Pedro; Bachireddy, Chethan; Grieco, A.; Ding, Rona; Leon, Samy J. Galvez de; Ulrich, Angela; Lama, Javier R.; Duerr, Ann; Altice, Frederick L.

doi:10.1097/qai.0000000000002889

Cited by 3 publications

(2 citation statements)

References 42 publications

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“…In Peru, there is an increase in heavy episodic drinking (i.e., binge drinking), and 14.0% of Peruvian males have an AUD [ 7 ]. AUD is thought to be more prevalent in PWH, especially MSM, due to alcohol’s disinhibitory effects that can lead to unsafe sex [ 8 , 9 ]. AUD in PWH has also been observed to have a negative influence on ART adherence and subsequent HIV management [ 8 , 9 ].…”

Section: Introductionmentioning

confidence: 99%

“…AUD is thought to be more prevalent in PWH, especially MSM, due to alcohol’s disinhibitory effects that can lead to unsafe sex [ 8 , 9 ]. AUD in PWH has also been observed to have a negative influence on ART adherence and subsequent HIV management [ 8 , 9 ]. Although AUD has been associated with non-communicable diseases (NCDs), there is sparse research into the extent to which AUD severity mitigates these NCDs, including oral diseases [ 10 , 11 ].…”

Section: Introductionmentioning

confidence: 99%

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Implementation of REDCap mobile app in an oral HIV clinical study

Seminario,

Karczewski,

Stanley

et al. 2024

BMC Public Health

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Background In Peru, HIV cases are highly concentrated among men who have sex with men (MSM). Despite the availability of anti-retroviral therapy, people living with HIV (PWH) have higher levels of oral diseases. Alcohol use disorder (AUD) is significantly present among PWH. Our overarching goal was to generate foundational evidence on the association of AUD and oral health in MSM with HIV and enhance research capacity for future intersectional research on AUD, oral health and HIV. Our specific aim was to implement an on-site electronic data collection system through the use of a REDCap Mobile App in a low-middle income country (LMIC) setting. Methods Five validated surveys were utilized to gather data on demographics, medical history, HIV status, alcohol use, HIV stigma, perceived oral health status, and dietary supplement use. These surveys were developed in REDCap and deployed with the REDCap Mobile App, which was installed on ten iPads across two medical HIV clinics in Lima, Peru. REDCap app as well as the protocol for data collection were calibrated with feedback from trial participants and clinical research staff to improve clinical efficiency and participant experience. Results The mean age of participants (n = 398) was 35.94 ± 9.13y, of which 98.5% identified as male, and 85.7% identified as homosexual. 78.1% of participants binge drank, and 12.3% reported being heavy drinkers. After pilot testing, significant modifications to the structure and layout of the surveys were performed to improve efficiency and flow. The app was successfully deployed to replace cumbersome paper records and collected data was directly stored in a REDCap database. Conclusions The REDCap Mobile App was successfully used due to its ability to: (a) capture and store data offline, (b) timely translate between multiple languages on the mobile app interface, and (c) provide user-friendly interface with low associated costs and ample support. Trial registration 1R56DE029639-01.

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